Millington is a city in Shelby County, Tennessee, United States, and is a part of the Memphis metropolitan area. As of the 2010 census, it had a population of 10,176. Millington was granted the title "Flag City Tennessee" by the Tennessee State Legislature. The Naval Support Activity Mid-South is located at the former Memphis Naval Air Station, whose function was changed in 1993 from a training base to an administrative one. There is also a general aviation airport that features the third longest runway in Tennessee.

The Memphis–Clarksdale-Forrest City Combined Statistical Area, TN–MS–AR (CSA) is the commercial and cultural hub of the Mid-South or Ark-Miss-Tenn. The census-defined combined statistical area covers eleven counties in three states, Tennessee, Mississippi, and Arkansas. As of 2020 census, the Memphis metropolitan area had a population of 1,389,905 The Forrest City, Arkansas Micropolitan area was added to the Memphis area in 2012 to form the Memphis–Forrest City Combined Statistical area. In 2023 the Clarksdale, Mississippi Micropolitan area was also added to form the new Memphis-Clarksdale-Forrest City Combined Statistical Area which as of 2023 had a population of roughly 1.4 million people according to census estimates.