A mineralocorticoid receptor antagonist or aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors. This group of drugs is often used as a
Antimineralocorticoids and highlighted groups that are important for activity. The y-lactone ring shown in red and the C-7 substituent in pink.
Spironolactone
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Spironolactone, sold under the brand name Aldactone among others, is classed as a diuretic medication. It can be used to treat fluid build-up due to liver disease or kidney disease. It is also used to
Mineralocorticoid receptor antagonist
…receptors. This group of drugs is often used as adjunctive therapy, in combination with other drugs, for the management of chronic heart failure. Spironolactone, the first member of the class, is also used in the management of hyperaldosteronism (including Conn's syndrome) and female hirsutism (due to additional…
Spironolactone 25 mg
Generic spironolactone for veterinary use