Spironolactone
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Spironolactone, sold under the brand name Aldactone among others, is classed as a diuretic medication. It can be used to treat fluid build-up due to liver disease or kidney disease. It is also used to
Spironolactone 25 mg
Generic spironolactone for veterinary use
A mineralocorticoid receptor antagonist or aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors. This group of drugs is often used as a
Spironolactone
…instance, in studies showing antidepressant-like effects of spironolactone in animals. The pharmacodynamics of spironolactone are characterized by high antimineralocorticoid activity, moderate antiandrogenic activity, and weak steroidogenesis inhibition, among other more minor activities. Spironolactone is a prodrug, so…
Antimineralocorticoids and highlighted groups that are important for activity. The y-lactone ring shown in red and the C-7 substituent in pink.