The Mingo people are an Iroquoian group of Native Americans, primarily Seneca and Cayuga, who migrated west from New York to the Ohio Country in the mid-18th century, and their descendants. Some Susquehannock survivors also joined them, and assimilated. Anglo-Americans called these migrants mingos, a corruption of mingwe, an Eastern Algonquian name for Iroquoian-language groups in general. The Mingo have also been called "Ohio Iroquois" and "Ohio Seneca".

The Cayuga are one of the five original constituents of the Haudenosaunee (Iroquois), a confederacy of Native Americans in New York. The Cayuga homeland lies in the Finger Lakes region along Cayuga Lake, between their league neighbors, the Onondaga to the east and the Seneca to the west. Today, Cayuga people belong to the Six Nations of the Grand River First Nation in Ontario, and the federally recognized Cayuga Nation of New York and the Seneca-Cayuga Tribe of Oklahoma.