The Federal Minister of Intra-German Relations was a federal cabinet minister of the Federal Republic of Germany. The office was created under the title of Federal Minister of All-German Affairs in 1949, being also in charge of the German lands east of the Oder–Neisse line which had been put under Polish or Soviet administration. In 1951, the first Minister of All-German Affairs Jakob Kaiser openly raised claim to even greater territories including Austria, parts of Switzerland, the Saar area and Alsace-Lorraine.

The Second Adenauer cabinet led by Konrad Adenauer was sworn in on 20 October 1953 after the 1953 elections. It laid down its function after the formation of the Cabinet Adenauer III on 29 October 1957, which was formed following the 1957 elections.