The Prime Minister of Monaco, literally the Minister of State, is the head of government of Monaco, being appointed by and subordinate to the Prince of Monaco.

Monaco, officially the Principality of Monaco, is a sovereign city-state and microstate on the French Riviera a few kilometres west of the Italian region of Liguria, in Western Europe, on the Mediterranean Sea. It is a semi-enclave bordered by France to the north, east and west. The principality is home to 38,682 residents, of whom 9,486 are Monégasque nationals; it is widely recognised as one of the wealthiest and most expensive places in the world. The official language of the principality is French. In addition, Monégasque, English and Italian are spoken and understood by many residents.