Monticello was the primary plantation of Thomas Jefferson, a Founding Father, author of the Declaration of Independence, and the third president of the United States, who began designing Monticello after inheriting land from his father at age 14. Located just outside Charlottesville, Virginia, in the Piedmont region, the plantation was originally 5,000 acres (20 km2), with Jefferson using the forced labor of Black slaves for extensive cultivation of tobacco and mixed crops, later shifting from tobacco cultivation to wheat in response to changing markets. Due to its architectural and historic significance, the property has been designated a National Historic Landmark. In 1987, Monticello and the nearby University of Virginia, also designed by Jefferson, were together designated a UNESCO World Heritage Site. The current nickel, a United States coin, features a depiction of Monticello on its reverse side.

The University of Virginia (UVA) is a public research university in Charlottesville, Virginia, United States. It was founded in 1819 by Thomas Jefferson and contains his Academical Village, a UNESCO World Heritage Site. The original governing Board of Visitors included three U.S. presidents: Jefferson, James Madison, and James Monroe, the latter as sitting president of the United States at the time of its foundation. As its first two rectors, Presidents Jefferson and Madison played key roles in the university's foundation, with Jefferson designing both the original courses of study and the university's architecture. Located within its historic 1,135-acre central campus, the university is composed of eight undergraduate and three professional schools: the School of Law, the Darden School of Business, and the School of Medicine.