Moose Creek is a census-designated place (CDP) in Fairbanks North Star Borough in the U.S. state of Alaska. As of the 2010 census, the population of the CDP was 747, up from 542 in 2000. It is part of the Fairbanks, Alaska Metropolitan Statistical Area. Moose Creek is located south of Fairbanks, Alaska along the Richardson Highway. Moose Creek is bordered by Eielson Air Force Base to the south, the Tanana River to the west, and the Chena River Flood Control Project to the north.

The Fairbanks North Star Borough is a borough located in the U.S. state of Alaska. As of the 2020 census, the population was 95,665, down from 97,581 in 2010. The borough seat is Fairbanks. The borough's land area is slightly smaller than that of the state of New Jersey.