Morgan City, Mississippi is a town in Leflore County along Mississippi Highway 7. The population was 255 at the 2010 census, down from 305 at the 2000 census. It is part of the Greenwood, Mississippi micropolitan area.

Leflore County is a county located in the U.S. state of Mississippi. As of the 2020 census, the population was 28,339. The county seat is Greenwood. The county is named for Choctaw leader Greenwood LeFlore, who signed a treaty to cede his people's land to the United States in exchange for land in Indian Territory. LeFlore stayed in Mississippi, settling on land reserved for him in Tallahatchie County.