A multi-instrumentalist is a musician who plays two or more musical instruments, often but not exclusively at a professional level of proficiency.

Eric Allan Dolphy Jr. was an American jazz multi-instrumentalist and bandleader. Primarily an alto saxophonist, bass clarinetist, and flautist, Dolphy was one of several multi-instrumentalists to gain prominence during the same era. His use of the bass clarinet helped to establish the unconventional instrument within jazz. Dolphy extended the vocabulary and boundaries of the alto saxophone, and was among the earliest significant jazz flute soloists.