1.
Leiden
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Leiden is a city and municipality in the Dutch province of South Holland. Leiden is located on the Oude Rijn, at a distance of some 20 kilometres from The Hague to its south, the recreational area of the Kaag Lakes lies just to the northeast of Leiden. A university city since 1575, Leiden houses Leiden University, the oldest university of the Netherlands, Leiden is a city with a rich cultural heritage, not only in science, but also in the arts. One of the worlds most famous painters, Rembrandt, was born, other famous Leiden painters include Lucas van Leyden, Jan van Goyen and Jan van Steen. The city has one of Europes most prominent scientific centres for more than four centuries. Modern scientific medical research and teaching started in the early 18th century in Leiden with Boerhaave, many important scientific discoveries have been made here, giving rise to Leiden’s motto, ‘City of Discoveries’. It is twinned with Oxford, the location of the United Kingdoms oldest university, Leiden University and Leiden University of Applied Sciences together have around 35,000 students. Leiden is a university city, university buildings are scattered throughout the city. Leiden was formed on a hill at the confluence of the rivers Oude. In the oldest reference to this, from circa 860, the settlement was called Leithon, the name is said to be from Germanic *leitha- canal. Leiden has in the past erroneously been associated with the Roman outpost Lugdunum Batavorum and this particular castellum was thought to be located at the Burcht of Leiden, and the citys name was thought to be derived of the Latin name Lugdunum. However the castellum was in closer to the town of Katwijk. The landlord of Leiden, situated in a stronghold on the hill, was subject to the Bishop of Utrecht. This county got its name in 1101 from a domain near the stronghold, Leiden was sacked in 1047 by Emperor Henry III. Early 13th century, Ada, Countess of Holland took refuge here when she was fighting in a war against her uncle, William I. He besieged the stronghold and captured Ada, Leiden received city rights in 1266. In 1389, its population had grown to about 4,000 persons, burgrave Filips of Wassenaar and the other local noblemen of the Hook faction assumed that the duke would besiege Leiden first and send small units out to conquer the surrounding citadels. But John of Bavaria chose to attack the citadels first and he rolled the cannons with his army but one which was too heavy went by ship
2.
Netherlands
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The Netherlands, also informally known as Holland is the main constituent country of the Kingdom of the Netherlands. It is a densely populated country located in Western Europe with three territories in the Caribbean. The European part of the Netherlands borders Germany to the east, Belgium to the south, and the North Sea to the northwest, sharing borders with Belgium, the United Kingdom. The three largest cities in the Netherlands are Amsterdam, Rotterdam and The Hague, Amsterdam is the countrys capital, while The Hague holds the Dutch seat of parliament and government. The port of Rotterdam is the worlds largest port outside East-Asia, the name Holland is used informally to refer to the whole of the country of the Netherlands. Netherlands literally means lower countries, influenced by its low land and flat geography, most of the areas below sea level are artificial. Since the late 16th century, large areas have been reclaimed from the sea and lakes, with a population density of 412 people per km2 –507 if water is excluded – the Netherlands is classified as a very densely populated country. Only Bangladesh, South Korea, and Taiwan have both a population and higher population density. Nevertheless, the Netherlands is the worlds second-largest exporter of food and agricultural products and this is partly due to the fertility of the soil and the mild climate. In 2001, it became the worlds first country to legalise same-sex marriage, the Netherlands is a founding member of the EU, Eurozone, G-10, NATO, OECD and WTO, as well as being a part of the Schengen Area and the trilateral Benelux Union. The first four are situated in The Hague, as is the EUs criminal intelligence agency Europol and this has led to the city being dubbed the worlds legal capital. The country also ranks second highest in the worlds 2016 Press Freedom Index, the Netherlands has a market-based mixed economy, ranking 17th of 177 countries according to the Index of Economic Freedom. It had the thirteenth-highest per capita income in the world in 2013 according to the International Monetary Fund, in 2013, the United Nations World Happiness Report ranked the Netherlands as the seventh-happiest country in the world, reflecting its high quality of life. The Netherlands also ranks joint second highest in the Inequality-adjusted Human Development Index, the region called Low Countries and the country of the Netherlands have the same toponymy. Place names with Neder, Nieder, Nether and Nedre and Bas or Inferior are in use in all over Europe. They are sometimes used in a relation to a higher ground that consecutively is indicated as Upper, Boven, Oben. In the case of the Low Countries / the Netherlands the geographical location of the region has been more or less downstream. The geographical location of the region, however, changed over time tremendously
3.
Douwe Breimer
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Douwe Durk Breimer is a Dutch pharmacologist and was both rector magnificus and president of the Executive Board of Leiden University, The Netherlands. Breimer studied pharmacology at the University of Groningen and obtained his Ph. D. from the Catholic University of Nijmegen, in 1975, he was appointed professor of pharmacology at Leiden University. His research focusses on pharmacokinetics, pharmacodynamics and drug metabolism, Breimer co-authored over 500 scientific papers and supervised more than 50 Ph. D. students. In 1987 he became member of the Royal Netherlands Academy of Arts and Sciences
4.
Leiden Centraal railway station
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Leiden Centraal is the main railway station in Leiden, a city in the Netherlands. Leiden Centraal station opened on 17 August 1842 as the terminal of the first expansion of the Old Line from Haarlem. The original building was replaced by a new one, designed by D. A. N and this station was later razed and replaced by a third station designed by HGJ Schelling. Due to its design, which was also implemented at other Dutch railway stations. Increasing numbers of passengers also caused the building to become overcrowded, the fourth, and current, station was designed by Harry Reijnders and completed in 1996. Consisting of a lattice structure, a curved, shell-like entrance leads into a ticketing hall lined with shops. When first built, the floor had a blue and white finish. Problems with passengers slipping required that the floor be replaced with standard tiling, in 2007, Leiden Centraal was renovated in accordance with the introduction of the OV-chipkaart, which created a nationwide smart card fare system. To implement the OV-chipkaart, ticket barriers were installed, separating the station into a paid and unpaid area, the platforms, waiting area, and several shops comprise the paid area, while the rest of the station is classified as unpaid. The barriers are open, as the new ticket system is still optional. On 28 November 2011, a Sprinter collided with a stationary Sprinter, NS website Dutch Public Transport journey planner
5.
History of science
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The history of science is the study of the development of science and scientific knowledge, including both the natural sciences and social sciences. Historiography of science, in contrast, studies the methods by which historians study the history of science, the English word scientist is relatively recent—first coined by William Whewell in the 19th century. Previously, people investigating nature called themselves natural philosophers, traditionally, historians of science have defined science sufficiently broadly to include those earlier inquiries. In prehistoric times, advice and knowledge was passed from generation to generation in an oral tradition, for example, the domestication of maize for agriculture has been dated to about 9,000 years ago in southern Mexico, before the development of writing systems. Similarly, archaeological evidence indicates the development of knowledge in preliterate societies. The development of writing enabled knowledge to be stored and communicated across generations with much greater fidelity, many ancient civilizations collected astronomical information in a systematic manner through simple observation. Though they had no knowledge of the physical structure of the planets and stars. Basic facts about human physiology were known in places. Considerable observation of flora and fauna was also performed. Ancient Egypt made significant advances in astronomy, mathematics and medicine and their development of geometry was a necessary outgrowth of surveying to preserve the layout and ownership of farmland, which was flooded annually by the Nile river. The 3-4-5 right triangle and other rules of geometry were used to build structures. Egypt was also a center of research for much of the Mediterranean. However, while Egyptian medicine had some practices, it was not without its ineffective. Medical historians believe that ancient Egyptian pharmacology, for example, was largely ineffective, E. R. Lloyd played a significant role in the development of this methodology. The Ebers papyrus also contains evidence of traditional empiricism, from their beginnings in Sumer around 3500 BC, the Mesopotamian people began to attempt to record some observations of the world with numerical data. But their observations and measurements were taken for purposes other than for elucidating scientific laws. A concrete instance of Pythagoras law was recorded, as early as the 18th century BC, dated 1900 BC, possibly millennia before Pythagoras, but an abstract formulation of the Pythagorean theorem was not. In Babylonian astronomy, records of the motions of the stars, planets, even today, astronomical periods identified by Mesopotamian proto-scientists are still widely used in Western calendars such as the solar year and the lunar month
6.
Medicine
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Medicine is the science and practice of the diagnosis, treatment, and prevention of disease. The word medicine is derived from Latin medicus, meaning a physician, Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Medicine has existed for thousands of years, during most of which it was an art frequently having connections to the religious and philosophical beliefs of local culture. For example, a man would apply herbs and say prayers for healing, or an ancient philosopher. In recent centuries, since the advent of modern science, most medicine has become a combination of art, while stitching technique for sutures is an art learned through practice, the knowledge of what happens at the cellular and molecular level in the tissues being stitched arises through science. Prescientific forms of medicine are now known as medicine and folk medicine. They remain commonly used with or instead of medicine and are thus called alternative medicine. For example, evidence on the effectiveness of acupuncture is variable and inconsistent for any condition, in contrast, treatments outside the bounds of safety and efficacy are termed quackery. Medical availability and clinical practice varies across the world due to differences in culture. In modern clinical practice, physicians personally assess patients in order to diagnose, treat, the doctor-patient relationship typically begins an interaction with an examination of the patients medical history and medical record, followed by a medical interview and a physical examination. Basic diagnostic medical devices are typically used, after examination for signs and interviewing for symptoms, the doctor may order medical tests, take a biopsy, or prescribe pharmaceutical drugs or other therapies. Differential diagnosis methods help to rule out conditions based on the information provided, during the encounter, properly informing the patient of all relevant facts is an important part of the relationship and the development of trust. The medical encounter is then documented in the record, which is a legal document in many jurisdictions. Follow-ups may be shorter but follow the general procedure. The diagnosis and treatment may take only a few minutes or a few weeks depending upon the complexity of the issue, the components of the medical interview and encounter are, Chief complaint, the reason for the current medical visit. They are in the patients own words and are recorded along with the duration of each one, also called chief concern or presenting complaint. History of present illness, the order of events of symptoms. Distinguishable from history of illness, often called past medical history
7.
Physics
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Physics is the natural science that involves the study of matter and its motion and behavior through space and time, along with related concepts such as energy and force. One of the most fundamental disciplines, the main goal of physics is to understand how the universe behaves. Physics is one of the oldest academic disciplines, perhaps the oldest through its inclusion of astronomy, Physics intersects with many interdisciplinary areas of research, such as biophysics and quantum chemistry, and the boundaries of physics are not rigidly defined. New ideas in physics often explain the mechanisms of other sciences while opening new avenues of research in areas such as mathematics. Physics also makes significant contributions through advances in new technologies that arise from theoretical breakthroughs, the United Nations named 2005 the World Year of Physics. Astronomy is the oldest of the natural sciences, the stars and planets were often a target of worship, believed to represent their gods. While the explanations for these phenomena were often unscientific and lacking in evidence, according to Asger Aaboe, the origins of Western astronomy can be found in Mesopotamia, and all Western efforts in the exact sciences are descended from late Babylonian astronomy. The most notable innovations were in the field of optics and vision, which came from the works of many scientists like Ibn Sahl, Al-Kindi, Ibn al-Haytham, Al-Farisi and Avicenna. The most notable work was The Book of Optics, written by Ibn Al-Haitham, in which he was not only the first to disprove the ancient Greek idea about vision, but also came up with a new theory. In the book, he was also the first to study the phenomenon of the pinhole camera, many later European scholars and fellow polymaths, from Robert Grosseteste and Leonardo da Vinci to René Descartes, Johannes Kepler and Isaac Newton, were in his debt. Indeed, the influence of Ibn al-Haythams Optics ranks alongside that of Newtons work of the same title, the translation of The Book of Optics had a huge impact on Europe. From it, later European scholars were able to build the devices as what Ibn al-Haytham did. From this, such important things as eyeglasses, magnifying glasses, telescopes, Physics became a separate science when early modern Europeans used experimental and quantitative methods to discover what are now considered to be the laws of physics. Newton also developed calculus, the study of change, which provided new mathematical methods for solving physical problems. The discovery of new laws in thermodynamics, chemistry, and electromagnetics resulted from greater research efforts during the Industrial Revolution as energy needs increased, however, inaccuracies in classical mechanics for very small objects and very high velocities led to the development of modern physics in the 20th century. Modern physics began in the early 20th century with the work of Max Planck in quantum theory, both of these theories came about due to inaccuracies in classical mechanics in certain situations. Quantum mechanics would come to be pioneered by Werner Heisenberg, Erwin Schrödinger, from this early work, and work in related fields, the Standard Model of particle physics was derived. Areas of mathematics in general are important to this field, such as the study of probabilities, in many ways, physics stems from ancient Greek philosophy
8.
Astronomy
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Astronomy is a natural science that studies celestial objects and phenomena. It applies mathematics, physics, and chemistry, in an effort to explain the origin of those objects and phenomena and their evolution. Objects of interest include planets, moons, stars, galaxies, and comets, while the phenomena include supernovae explosions, gamma ray bursts, more generally, all astronomical phenomena that originate outside Earths atmosphere are within the purview of astronomy. A related but distinct subject, physical cosmology, is concerned with the study of the Universe as a whole, Astronomy is the oldest of the natural sciences. The early civilizations in recorded history, such as the Babylonians, Greeks, Indians, Egyptians, Nubians, Iranians, Chinese, during the 20th century, the field of professional astronomy split into observational and theoretical branches. Observational astronomy is focused on acquiring data from observations of astronomical objects, theoretical astronomy is oriented toward the development of computer or analytical models to describe astronomical objects and phenomena. The two fields complement each other, with theoretical astronomy seeking to explain the results and observations being used to confirm theoretical results. Astronomy is one of the few sciences where amateurs can play an active role, especially in the discovery. Amateur astronomers have made and contributed to many important astronomical discoveries, Astronomy means law of the stars. Astronomy should not be confused with astrology, the system which claims that human affairs are correlated with the positions of celestial objects. Although the two share a common origin, they are now entirely distinct. Generally, either the term astronomy or astrophysics may be used to refer to this subject, however, since most modern astronomical research deals with subjects related to physics, modern astronomy could actually be called astrophysics. Few fields, such as astrometry, are purely astronomy rather than also astrophysics, some titles of the leading scientific journals in this field includeThe Astronomical Journal, The Astrophysical Journal and Astronomy and Astrophysics. In early times, astronomy only comprised the observation and predictions of the motions of objects visible to the naked eye, in some locations, early cultures assembled massive artifacts that possibly had some astronomical purpose. Before tools such as the telescope were invented, early study of the stars was conducted using the naked eye, most of early astronomy actually consisted of mapping the positions of the stars and planets, a science now referred to as astrometry. From these observations, early ideas about the motions of the planets were formed, and the nature of the Sun, Moon, the Earth was believed to be the center of the Universe with the Sun, the Moon and the stars rotating around it. This is known as the model of the Universe, or the Ptolemaic system. The Babylonians discovered that lunar eclipses recurred in a cycle known as a saros
9.
Anatomical theatre
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An anatomical theatre was an institution used in teaching anatomy at early modern universities. The theatre was usually a room of roughly amphitheatrical shape, in the centre of which would stand the table on which the dissections of human or animal bodies took place, the first anatomical theatre was built at the University of Padua in 1594 and is still preserved. Other early examples include the Theatrum Anatomicum of Leiden University, built in 1596 and reconstructed in 1988, rudbeck had spent time in Leiden, and both the anatomical theatre and the botanical garden he founded in Uppsala in 1655 were influenced by his experiences there. Today Gustavianum is open for the public under the name Museum Gustavianum, thomas Jefferson built an anatomical theatre for the University of Virginia. It was completed in 1827 but demolished in 1939 after the construction of Alderman Library nearby, - A model of the anatomical theatre in Padua Anatomical Theatre. - Engraving of the theatre at Leiden University. The history of Bologna Universitys Medical School over the centuries, acta Dermatovenerologica Alpina, Pannonica et Adriatica. Archived from the original on 3 December 2005, - with an image of the Renaissance anatomical theatre at the Bologna University Digging in the Dirt. Retrieved December 15,2005. - has a section on Jeffersons anatomical theatre Anatomical Theatre, institute for Advanced Technology in the Humanities
10.
Heike Kamerlingh Onnes
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Heike Kamerlingh Onnes was a Dutch physicist and Nobel laureate. He exploited the Hampson-Linde cycle to investigate how materials behave when cooled to nearly absolute zero and his production of extreme cryogenic temperatures led to his discovery of superconductivity in 1911, for certain materials, electrical resistance abruptly vanishes at very low temperatures. Kamerlingh Onnes was born in Groningen, Netherlands and his father, Harm Kamerlingh Onnes, was a brickworks owner. His mother was Anna Gerdina Coers of Arnhem, in 1870, Kamerlingh Onnes attended the University of Groningen. He studied under Robert Bunsen and Gustav Kirchhoff at the University of Heidelberg from 1871 to 1873, again at Groningen, he obtained his masters in 1878 and a doctorate in 1879. His thesis was Nieuwe bewijzen voor de aswenteling der aarde, from 1878 to 1882 he was assistant to Johannes Bosscha, the director of the Delft Polytechnic, for whom he substituted as lecturer in 1881 and 1882. He was married to Maria Adriana Wilhelmina Elisabeth Bijleveld and had one child and his brother Menso Kamerlingh Onnes was a fairly well known painter, while his sister Jenny married another famous painter, Floris Verster. From 1882 to 1923 Kamerlingh Onnes served as professor of physics at the University of Leiden. In 1904 he founded a very large cryogenics laboratory and invited other researchers to the location, the laboratory is known now as Kamerlingh Onnes Laboratory. Only one year after his appointment as professor he became member of the Royal Netherlands Academy of Arts, on 10 July 1908, he was the first to liquefy helium, using several precooling stages and the Hampson-Linde cycle based on the Joule-Thomson effect. This way he lowered the temperature to the point of helium. By reducing the pressure of the liquid helium he achieved a temperature near 1.5 K and these were the coldest temperatures achieved on earth at the time. The equipment employed is at the Boerhaave Museum in Leiden, in 1911 Kamerlingh Onnes measured the electrical conductivity of pure metals at very low temperatures. Others, including Kamerlingh Onnes, felt that an electrical resistance would steadily decrease. On 8 April 1911, Kamerlingh Onnes found that at 4.2 K the resistance in a solid mercury wire immersed in liquid helium suddenly vanished and he immediately realized the significance of the discovery. He reported that Mercury has passed into a new state, which on account of its electrical properties may be called the superconductive state. He published more articles about the phenomenon, initially referring to it as supraconductivity and, some of the instruments he devised for his experiments can be seen at the Boerhaave Museum in Leiden. The apparatus he used to first liquefy helium is on display in the lobby of the department at Leiden University
11.
Helium
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Helium is a chemical element with symbol He and atomic number 2. It is a colorless, odorless, tasteless, non-toxic, inert, monatomic gas and its boiling point is the lowest among all the elements. Its abundance is similar to figure in the Sun and in Jupiter. This is due to the high nuclear binding energy of helium-4 with respect to the next three elements after helium. This helium-4 binding energy also accounts for why it is a product of nuclear fusion and radioactive decay. Most helium in the universe is helium-4, and is believed to have formed during the Big Bang. Large amounts of new helium are being created by fusion of hydrogen in stars. Helium is named for the Greek god of the Sun, Helios and it was first detected as an unknown yellow spectral line signature in sunlight during a solar eclipse in 1868 by French astronomer Jules Janssen. Janssen is jointly credited with detecting the element along with Norman Lockyer, Janssen observed during the solar eclipse of 1868 while Lockyer observed from Britain. Lockyer was the first to propose that the line was due to a new element, the formal discovery of the element was made in 1895 by two Swedish chemists, Per Teodor Cleve and Nils Abraham Langlet, who found helium emanating from the uranium ore cleveite. In 1903, large reserves of helium were found in gas fields in parts of the United States. Liquid helium is used in cryogenics, particularly in the cooling of superconducting magnets, a well-known but minor use is as a lifting gas in balloons and airships. As with any gas whose density differs from that of air, inhaling a small volume of helium temporarily changes the timbre, on Earth it is relatively rare—5.2 ppm by volume in the atmosphere. Most terrestrial helium present today is created by the radioactive decay of heavy radioactive elements. Previously, terrestrial helium—a non-renewable resource, because once released into the atmosphere it readily escapes into space—was thought to be in short supply. The first evidence of helium was observed on August 18,1868, the line was detected by French astronomer Jules Janssen during a total solar eclipse in Guntur, India. This line was assumed to be sodium. He concluded that it was caused by an element in the Sun unknown on Earth, Lockyer and English chemist Edward Frankland named the element with the Greek word for the Sun, ἥλιος
12.
Leyden jar
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A Leyden jar, or Leiden jar, is a device that stores static electricity between two electrodes on the inside and outside of a glass jar. It was the form of a capacitor. It was invented independently by German cleric Ewald Georg von Kleist on 11 October 1745, the invention was named after the city. The Leyden jar was used to conduct many experiments in electricity. The Leyden jar was the first means of storing an electric charge which then could be discharged at the experimenters will, Leyden jars are still used in education to demonstrate the principles of electrostatics. The Ancient Greeks already knew that pieces of amber could attract lightweight particles after being rubbed, the amber becomes electrified by triboelectric effect, mechanical separation of charge in a dielectric. The Greek word for amber is ηλεκτρον and is the origin of the word electricity, around 1650, Otto von Guericke built a crude electrostatic generator, a sulphur ball that rotated on a shaft. When Guericke held his hand against the ball and turned the shaft quickly and this experiment inspired the development of several forms of friction machines, that greatly helped in the study of electricity. Despite its mundane and safe appearance, the Leyden jar is a high voltage device, the ball on the tip of the rod is a corona ball to prevent leakage of the energy into the air by point discharge. He was the deacon at the cathedral of Camin in Pomerania, in 1744 von Kleist tried to accumulate electricity in a small medicine bottle filled with alcohol with a nail inserted in the cork. He was following up on an experiment developed by Georg Matthias Bose where electricity had been sent though water to set alcoholic spirits alight and he attempted to charge the bottle from a large prime conductor suspended above his friction machine. Kleist was convinced that an electric charge could be collected. He received a significant shock from the device when he touched the nail through the cork while still cradling the bottle in his other hand. It took some time before Kleists student associates at Leyden worked out that the hand provided an essential element, Andreas Cuneaus, appears to have been the first to receive communications from von Kleist about the storage capacity of the jar. He attempted to duplicate the experiment using a glass of beer, Cunaeus and Musschenbroek also received severe shocks, and Musschenbroek communicated the experiment to Abbé Nollet, René Antoine Ferchault de Réaumur, and the wider French scientific community. Musschenbroeks outlet in France for the sale of his companys cabinet devices was the Abbé Nollet, Nollet then gave the electrical storage device the name Leyden Jar and promoted it as a special type of flask to his market of wealthy men with scientific curiosity. The Kleistian jar was therefore promoted as the Leyden Jar as having been discovered by Pieter van Musschenbroek, daniel Gralath was the first to connect several jars in parallel to increase the total possible stored charge. The term battery was coined by Benjamin Franklin for these combinations, the term was later used for combinations of multiple electrochemical cells, the modern meaning of the term battery
13.
Herman Boerhaave
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Herman Boerhaave was a Dutch botanist, chemist, Christian humanist and physician of European fame. He is best known for demonstrating the relation of symptoms to lesions and, in addition and he was the first physician that put thermometer measurements to clinical practice. His motto was Simplex sigillum veri, The simple is the sign of the true and he is often hailed as the Dutch Hippocrates. Boerhaave was born at Voorhout near Leiden, the son of a Protestant pastor, in his youth Boerhaave studied for a divinity degree and wanted to become a preacher. There he attacked the doctrines of Epicurus, Thomas Hobbes and Spinoza and he then turned to the study of medicine, in which he graduated in 1693 at Harderwijk in present-day Gelderland. On 14 September 1710, Boerhaave married Maria Drolenvaux, the daughter of the rich merchant and they had four children, of whom one daughter, Maria Joanna, lived to adulthood. In 1722, he began to suffer from a case of gout. In 1714, when he was appointed rector of the university, he succeeded Govert Bidloo in the chair of practical medicine, four years later he was appointed to the chair of chemistry as well. In 1728 he was elected into the French Academy of Sciences, in 1729 declining health obliged him to resign the chairs of chemistry and botany, and he died, after a lingering and painful illness, at Leiden. His reputation so increased the fame of the University of Leiden, especially as a school of medicine, all the princes of Europe sent him pupils, who found in this skillful professor not only an indefatigable teacher, but an affectionate guardian. When Peter the Great went to Holland in 1716, he took lessons from Boerhaave. Voltaire traveled to see him, as did Carl Linnaeus, who became a close friend and his reputation was not confined to Europe, a Chinese mandarin sent him a letter addressed to the illustrious Boerhaave, physician in Europe, and it reached him in due course. The operating theatre of the University of Leiden in which he worked as an anatomist is now at the center of a museum named after him. Asteroid 8175 Boerhaave is named after Boerhaave, from 1955 to 1961 Boerhaaves image was printed on Dutch 20-guilder banknotes. The Leiden University Medical Centre organises medical trainings called Boerhaave-courses and he had a prodigious influence on the development of medicine and chemistry in Scotland. British medical schools credit Boerhaave for developing the system of medical education upon which their current institutions are based, every founding member of the Edinburgh Medical School had studied at Leyden and attended Boerhaaves lectures on chemistry including John Rutherford and Francis Home. Boerhaaves Elementa Chemiae is recognized as the first text on chemistry, Boerhaave first described Boerhaave syndrome, which involves tearing of the esophagus, usually a consequence of vigorous vomiting. He notoriously described in 1724 the case of Baron Jan von Wassenaer and this condition was uniformly fatal prior to modern surgical techniques allowing repair of the esophagus
14.
Peter the Great
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Peter the Great, Peter I or Peter Alexeyevich ruled the Tsardom of Russia and later the Russian Empire from 7 May 1682 until his death, jointly ruling before 1696 with his elder half-brother, Ivan V. Through a number of successful wars he expanded the Tsardom into a larger empire that became a major European power. He led a revolution that replaced some of the traditionalist and medieval social and political systems with ones that were modern, scientific, westernized. Peters reforms made an impact on Russia and many institutions of Russian government trace their origins to his reign. From an early age, Peters education was put in the hands of tutors, most notably Nikita Zotov, Patrick Gordon. On 29 January 1676, Tsar Alexis died, leaving the sovereignty to Peters elder half-brother and this position changed when Feodor died in 1682. As Feodor did not leave any children, a dispute arose between the Miloslavsky family and Naryshkin family over who should inherit the throne, Peters other half-brother, Ivan V, was next in line for the throne, but he was chronically ill and of infirm mind. Consequently, the Boyar Duma chose the 10-year-old Peter to become Tsar with his mother as regent and this arrangement was brought before the people of Moscow, as ancient tradition demanded, and was ratified. Sophia Alekseyevna, one of Alexis daughters from his first marriage, in the subsequent conflict some of Peters relatives and friends were murdered, including Matveev, and Peter witnessed some of these acts of political violence. The Streltsy made it possible for Sophia, the Miloslavskys and their allies, to insist that Peter and Ivan be proclaimed joint Tsars, Sophia acted as regent during the minority of the sovereigns and exercised all power. For seven years, she ruled as an autocrat, a large hole was cut in the back of the dual-seated throne used by Ivan and Peter. Sophia would sit behind the throne and listen as Peter conversed with nobles, while feeding him information and giving him responses to questions and this throne can be seen in the Kremlin Armoury in Moscow. Peter was not particularly concerned that others ruled in his name and he engaged in such pastimes as shipbuilding and sailing, as well as mock battles with his toy army. Peters mother sought to force him to adopt a conventional approach. The marriage was a failure, and ten years later Peter forced his wife to become a nun, by the summer of 1689, Peter planned to take power from his half-sister Sophia, whose position had been weakened by two unsuccessful Crimean campaigns. When she learned of his designs, Sophia conspired with the leaders of the Streltsy, Sophia was eventually overthrown, with Peter I and Ivan V continuing to act as co-tsars. Peter forced Sophia to enter a convent, where she gave up her name, still, Peter could not acquire actual control over Russian affairs. Power was instead exercised by his mother, Natalya Naryshkina and it was only when Nataliya died in 1694 that Peter became an independent sovereign
15.
Voltaire
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Voltaire was a versatile writer, producing works in almost every literary form, including plays, poems, novels, essays, and historical and scientific works. He wrote more than 21,000 letters and over two books and pamphlets. He was an advocate of civil liberties, despite the risk this placed him in under the strict censorship laws of the time. As a satirical polemicist, he made use of his works to criticize intolerance, religious dogma. Some speculation surrounds Voltaires date of birth, because he claimed he was born on 20 February 1694 as the son of a nobleman. Two of his older brothers—Armand-François and Robert—died in infancy and his brother, Armand. Nicknamed Zozo by his family, Voltaire was baptized on 22 November 1694, with François de Castagnère, abbé de Châteauneuf, and Marie Daumard, the wife of his mothers cousin, standing as godparents. He was educated by the Jesuits at the Collège Louis-le-Grand, where he was taught Latin, theology, and rhetoric, later in life he became fluent in Italian, Spanish, and English. By the time he left school, Voltaire had decided he wanted to be a writer, against the wishes of his father, Voltaire, pretending to work in Paris as an assistant to a notary, spent much of his time writing poetry. When his father out, he sent Voltaire to study law. Nevertheless, he continued to write, producing essays and historical studies, Voltaires wit made him popular among some of the aristocratic families with whom he mixed. In 1713, his father obtained a job for him as a secretary to the new French ambassador in the Netherlands, the marquis de Châteauneuf, at The Hague, Voltaire fell in love with a French Protestant refugee named Catherine Olympe Dunoyer. Their scandalous affair was discovered by de Châteauneuf and Voltaire was forced to return to France by the end of the year, Most of Voltaires early life revolved around Paris. From early on, Voltaire had trouble with the authorities for critiques of the government and these activities were to result in two imprisonments and a temporary exile to England. One satirical verse, in which Voltaire accused the Régent of incest with his own daughter, the Comédie-Française had agreed in January 1717 to stage his debut play, Œdipe, and it opened in mid-November 1718, seven months after his release. Its immediate critical and financial success established his reputation, both the Régent and King George I of Great Britain presented Voltaire with medals as a mark of their appreciation. He mainly argued for tolerance and freedom of thought. He campaigned to eradicate priestly and aristo-monarchical authority, and supported a constitutional monarchy that protects peoples rights, the author adopted the name Voltaire in 1718, following his incarceration at the Bastille
16.
Carl Linnaeus
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Carl Linnaeus, also known after his ennoblement as Carl von Linné, was a Swedish botanist, physician, and zoologist, who formalised the modern system of naming organisms called binomial nomenclature. He is known by the father of modern taxonomy. Many of his writings were in Latin, and his name is rendered in Latin as Carolus Linnæus, Linnaeus was born in the countryside of Småland, in southern Sweden. He received most of his education at Uppsala University. He lived abroad between 1735 and 1738, where he studied and also published a first edition of his Systema Naturae in the Netherlands and he then returned to Sweden, where he became professor of medicine and botany at Uppsala. In the 1740s, he was sent on journeys through Sweden to find and classify plants. In the 1750s and 1760s, he continued to collect and classify animals, plants, and minerals, at the time of his death, he was one of the most acclaimed scientists in Europe. The philosopher Jean-Jacques Rousseau sent him the message, Tell him I know no man on earth. The German writer Johann Wolfgang von Goethe wrote, With the exception of Shakespeare and Spinoza, Swedish author August Strindberg wrote, Linnaeus was in reality a poet who happened to become a naturalist. Among other compliments, Linnaeus has been called Princeps botanicorum, The Pliny of the North and he is also considered as one of the founders of modern ecology. In botany, the abbreviation used to indicate Linnaeus as the authority for species names is L. In older publications, sometimes the abbreviation Linn. is found, Linnæus was born in the village of Råshult in Småland, Sweden, on 23 May 1707. He was the first child of Nicolaus Ingemarsson and Christina Brodersonia and his siblings were Anna Maria Linnæa, Sofia Juliana Linnæa, Samuel Linnæus, and Emerentia Linnæa. One of a line of peasants and priests, Nils was an amateur botanist, a Lutheran minister. Christina was the daughter of the rector of Stenbrohult, Samuel Brodersonius, a year after Linnæus birth, his grandfather Samuel Brodersonius died, and his father Nils became the rector of Stenbrohult. The family moved into the rectory from the curates house, even in his early years, Linnæus seemed to have a liking for plants, flowers in particular. Whenever he was upset, he was given a flower, which calmed him. Nils spent much time in his garden and often showed flowers to Linnaeus, soon Linnæus was given his own patch of earth where he could grow plants
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Leiden University
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Leiden University, located in the city of Leiden, is the oldest university in the Netherlands. The university was founded in 1575 by William, Prince of Orange, the Dutch Royal Family and Leiden University still have a close relationship, Queens Juliana and Beatrix and King Willem-Alexander are all former students. Leiden University has seven faculties, over 50 departments and enjoys an international reputation. Shanghai Jiao Tong Universitys 2011 Academic Ranking of World Universities ranked Leiden University as the 29th best university worldwide, the Times Higher Education World University Rankings consistently rank Leiden University as the best university in Continental Europe for Arts and Humanities. During this time Leiden was home to figures as René Descartes, Rembrandt, Christiaan Huygens, Hugo Grotius, Baruch Spinoza. The university is a member of the Coimbra Group, the Europaeum, Leiden University houses more than 40 national and international research institutes. In 1575, the emerging Dutch Republic did not have any universities in its northern heartland, the only other university in the Habsburg Netherlands was the University of Leuven in southern Leuven, firmly under Spanish control. It is said the choice fell on Leiden as a reward for the defence of Leiden against Spanish attacks in the previous year. Ironically, the name of Philip II of Spain, Williams adversary, appears on the foundation certificate. Philip II replied by forbidding any subject to study in Leiden, renowned philosopher Baruch Spinoza was based close to Leiden during this period and interacted with numerous scholars at the university. At the end of the century, Leiden University again became one of Europes leading universities. At the world’s first university low-temperature laboratory, professor Heike Kamerlingh Onnes achieved temperatures of one degree above absolute zero of −273 degrees Celsius. In 1908 he was also the first to succeed in liquifying helium, Kamerlingh Onnes was awarded the Nobel Prize for Physics in 1913. In 2005 the manuscript of Einstein on the theory of the monatomic ideal gas was discovered in one of Leidens libraries. Of the seventy-seven Spinozapremie, nineteen were granted to professors of the Universiteit Leiden, literary historian Frits van Oostrom was the first professor of Leiden to be granted the Spinoza award for his work on developing the NLCM centre into a top research centre. Among other leading professors are Wim Blockmans, professor of Medieval History, the portraits of many famous professors since the earliest days hang in the university aula, one of the most memorable places, as Niebuhr called it, in the history of science. The University Library, which has more than 5 and it houses the largest collections worldwide on Indonesia and the Caribbean. Scholars from all over the world visit Leiden University Library, the oldest in the Netherlands, the anatomical and pathological laboratories of the university are modern, and the museums of geology and mineralogy have been restored
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Chemistry
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Chemistry is a branch of physical science that studies the composition, structure, properties and change of matter. Chemistry is sometimes called the science because it bridges other natural sciences, including physics. For the differences between chemistry and physics see comparison of chemistry and physics, the history of chemistry can be traced to alchemy, which had been practiced for several millennia in various parts of the world. The word chemistry comes from alchemy, which referred to a set of practices that encompassed elements of chemistry, metallurgy, philosophy, astrology, astronomy, mysticism. An alchemist was called a chemist in popular speech, and later the suffix -ry was added to this to describe the art of the chemist as chemistry, the modern word alchemy in turn is derived from the Arabic word al-kīmīā. In origin, the term is borrowed from the Greek χημία or χημεία and this may have Egyptian origins since al-kīmīā is derived from the Greek χημία, which is in turn derived from the word Chemi or Kimi, which is the ancient name of Egypt in Egyptian. Alternately, al-kīmīā may derive from χημεία, meaning cast together, in retrospect, the definition of chemistry has changed over time, as new discoveries and theories add to the functionality of the science. The term chymistry, in the view of noted scientist Robert Boyle in 1661, in 1837, Jean-Baptiste Dumas considered the word chemistry to refer to the science concerned with the laws and effects of molecular forces. More recently, in 1998, Professor Raymond Chang broadened the definition of chemistry to mean the study of matter, early civilizations, such as the Egyptians Babylonians, Indians amassed practical knowledge concerning the arts of metallurgy, pottery and dyes, but didnt develop a systematic theory. Greek atomism dates back to 440 BC, arising in works by such as Democritus and Epicurus. In 50 BC, the Roman philosopher Lucretius expanded upon the theory in his book De rerum natura, unlike modern concepts of science, Greek atomism was purely philosophical in nature, with little concern for empirical observations and no concern for chemical experiments. Work, particularly the development of distillation, continued in the early Byzantine period with the most famous practitioner being the 4th century Greek-Egyptian Zosimos of Panopolis. He formulated Boyles law, rejected the four elements and proposed a mechanistic alternative of atoms. Before his work, though, many important discoveries had been made, the Scottish chemist Joseph Black and the Dutchman J. B. English scientist John Dalton proposed the theory of atoms, that all substances are composed of indivisible atoms of matter. Davy discovered nine new elements including the alkali metals by extracting them from their oxides with electric current, british William Prout first proposed ordering all the elements by their atomic weight as all atoms had a weight that was an exact multiple of the atomic weight of hydrogen. The inert gases, later called the noble gases were discovered by William Ramsay in collaboration with Lord Rayleigh at the end of the century, thereby filling in the basic structure of the table. Organic chemistry was developed by Justus von Liebig and others, following Friedrich Wöhlers synthesis of urea which proved that organisms were, in theory
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Botany
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Botany, also called plant science, plant biology or phytology, is the science of plant life and a branch of biology. A botanist or plant scientist is a scientist who specialises in this field, the term botany comes from the Ancient Greek word βοτάνη meaning pasture, grass, or fodder, βοτάνη is in turn derived from βόσκειν, to feed or to graze. Nowadays, botanists study approximately 410,000 species of plants of which some 391,000 species are vascular plants. Medieval physic gardens, often attached to monasteries, contained plants of medical importance and they were forerunners of the first botanical gardens attached to universities, founded from the 1540s onwards. One of the earliest was the Padua botanical garden and these gardens facilitated the academic study of plants. Efforts to catalogue and describe their collections were the beginnings of plant taxonomy, in the last two decades of the 20th century, botanists exploited the techniques of molecular genetic analysis, including genomics and proteomics and DNA sequences to classify plants more accurately. Modern botany is a broad, multidisciplinary subject with inputs from most other areas of science, dominant themes in 21st century plant science are molecular genetics and epigenetics, which are the mechanisms and control of gene expression during differentiation of plant cells and tissues. Botany originated as herbalism, the study and use of plants for their medicinal properties, many records of the Holocene period date early botanical knowledge as far back as 10,000 years ago. This early unrecorded knowledge of plants was discovered in ancient sites of human occupation within Tennessee, the early recorded history of botany includes many ancient writings and plant classifications. Examples of early works have been found in ancient texts from India dating back to before 1100 BC, in archaic Avestan writings. His major works, Enquiry into Plants and On the Causes of Plants, constitute the most important contributions to science until the Middle Ages. De Materia Medica was widely read for more than 1,500 years, important contributions from the medieval Muslim world include Ibn Wahshiyyas Nabatean Agriculture, Abū Ḥanīfa Dīnawarīs the Book of Plants, and Ibn Bassals The Classification of Soils. In the early 13th century, Abu al-Abbas al-Nabati, and Ibn al-Baitar wrote on botany in a systematic and scientific manner and these gardens continued the practical value of earlier physic gardens, often associated with monasteries, in which plants were cultivated for medical use. They supported the growth of botany as an academic subject, lectures were given about the plants grown in the gardens and their medical uses demonstrated. Botanical gardens came much later to northern Europe, the first in England was the University of Oxford Botanic Garden in 1621, throughout this period, botany remained firmly subordinate to medicine. German physician Leonhart Fuchs was one of the three German fathers of botany, along with theologian Otto Brunfels and physician Hieronymus Bock, Fuchs and Brunfels broke away from the tradition of copying earlier works to make original observations of their own. Bock created his own system of plant classification, physician Valerius Cordus authored a botanically and pharmacologically important herbal Historia Plantarum in 1544 and a pharmacopoeia of lasting importance, the Dispensatorium in 1546. Naturalist Conrad von Gesner and herbalist John Gerard published herbals covering the medicinal uses of plants, naturalist Ulisse Aldrovandi was considered the father of natural history, which included the study of plants
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Zoology
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The term is derived from Ancient Greek ζῷον, zōion, i. e. animal and λόγος, logos, i. e. knowledge, study. The history of zoology traces the study of the kingdom from ancient to modern times. This ancient work was developed in the Middle Ages by Muslim physicians. During the Renaissance and early period, zoological thought was revolutionized in Europe by a renewed interest in empiricism. Microscopy revealed the unknown world of microorganisms, laying the groundwork for cell theory. The growing importance of natural theology, partly a response to the rise of mechanical philosophy, over the 18th and 19th centuries, zoology became an increasingly professional scientific discipline. Naturalists began to reject essentialism and consider the importance of extinction, cell theory provided a new perspective on the fundamental basis of life. These developments, as well as the results from embryology and paleontology, were synthesized in Charles Darwins theory of evolution by natural selection. In 1859, Darwin placed the theory of evolution on a new footing, by his discovery of a process by which organic evolution can occur. Darwin gave new direction to morphology and physiology, by uniting them in a biological theory. The end of the 19th century saw the fall of spontaneous generation, cell biology studies the structural and physiological properties of cells, including their behavior, interactions, and environment. This is done on both the microscopic and molecular levels, for single-celled organisms such as bacteria as well as the cells in multicellular organisms such as humans. Understanding the structure and function of cells is fundamental to all of the biological sciences, the similarities and differences between cell types are particularly relevant to molecular biology. Anatomy considers the forms of macroscopic structures such as organs and organ systems and it focuses on how organs and organ systems work together in the bodies of humans and animals, in addition to how they work independently. Anatomy and cell biology are two studies that are related, and can be categorized under structural studies. Physiology studies the mechanical, physical, and biochemical processes of living organisms by attempting to understand how all of the function as a whole. The theme of structure to function is central to biology, for example, what is learned about the physiology of yeast cells can also apply to human cells. The field of animal physiology extends the tools and methods of physiology to non-human species
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Pharmacy
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Pharmacy is the science and technique of preparing and dispensing drugs. It is a profession that links health sciences with chemical sciences and aims to ensure the safe. Pharmacists, therefore, are the experts on drug therapy and are the health professionals who optimize use of medication for the benefit of the patients. An establishment in which pharmacy is practiced is called a pharmacy or a chemists, often, collaborative teams from various disciplines work together toward the introduction of new therapeutics and methods for patient care. However, pharmacy is not a basic or biomedical science in its typical form, medicinal chemistry is also a distinct branch of synthetic chemistry combining pharmacology, organic chemistry, and chemical biology. Pharmacology is sometimes considered as the 4th discipline of pharmacy, although pharmacology is essential to the study of pharmacy, it is not specific to pharmacy. Both disciplines are distinct. Those who wish to practice both pharmacy and pharmacology receive separate training and degrees unique to either discipline, pharmacoinformatics is considered another new discipline, for systematic drug discovery and development with efficiency and safety. The World Health Organization estimates that there are at least 2.6 million pharmacists, pharmacists are healthcare professionals with specialised education and training who perform various roles to ensure optimal health outcomes for their patients through the quality use of medicines. Pharmacists may also be small-business proprietors, owning the pharmacy in which they practice, pharmacists are represented internationally by the International Pharmaceutical Federation. In some cases, the body is also the registering body. The Commission for Certification in Geriatric Pharmacy certifies pharmacists in geriatric pharmacy practice, the American Board of Applied Toxicology certifies pharmacists and other medical professionals in applied toxicology. A Pharmacy Technician in the UK has recently referred to by some as a professional. Legislation requires the supervision of certain pharmacy technicians activities by a pharmacist, the majority of pharmacy technicians work in community pharmacies. In hospital pharmacies, pharmacy technicians may be managed by other senior pharmacy technicians, Pharmacy technicians are registered with the General Pharmaceutical Council. The GPhC is the regulator of pharmacists, pharmacy technicians and pharmacy premises, in the US, pharmacy technicians perform their duties under supervision of pharmacists. The earliest known compilation of medicinal substances was the Sushruta Samhita, however, the earliest text as preserved dates to the 3rd or 4th century AD. Many Sumerian cuneiform clay tablets record prescriptions for medicine, Ancient Egyptian pharmacological knowledge was recorded in various papyri such as the Ebers Papyrus of 1550 BC, and the Edwin Smith Papyrus of the 16th century BC. In Ancient Greece, Diocles of Carystus was one of several men studying the properties of plants
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Physiology
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Physiology is the scientific study of normal mechanisms, and their interactions, which operate within a living system. A sub-discipline of biology, its focus is in how organisms, organ systems, organs, cells, and biomolecules carry out the chemical or physical functions that exist in a living system. Given the size of the field, it is divided into, among others, animal physiology, plant physiology, cellular physiology, microbial physiology, bacterial physiology, and viral physiology. The Nobel Prize in Physiology or Medicine is awarded to those who make significant achievements in this discipline by the Royal Swedish Academy of Sciences. In medicine, a state is one occurring from normal body function, rather than pathologically. Physiological studies date back to the ancient civilizations of India and Egypt alongside anatomical studies, the study of human physiology as a medical field dates back to at least 420 BC to the time of Hippocrates, also known as the father of medicine. Hippocrates incorporated his belief called the theory of humours, which consisted of four basic substance, earth, water, air. Each substance is known for having a corresponding humour, black bile, phlegm, blood and yellow bile, Hippocrates also noted some emotional connections to the four humours, which Claudis Galenus would later expand on. The critical thinking of Aristotle and his emphasis on the relationship between structure and function marked the beginning of physiology in Ancient Greece. Like Hippocrates, Aristotle took to the theory of disease. Claudius Galenus, known as Galen of Pergamum, was the first to use experiments to probe the functions of the body, unlike Hippocrates though, Galen argued that humoral imbalances can be located in specific organs, including the entire body. His modification of this theory better equipped doctors to more precise diagnoses. Galen was also the founder of experimental physiology, and for the next 1,400 years, Galenic physiology was a powerful and influential tool in medicine. Jean Fernel, a French physician, introduced the term physiology, inspired in the work of Adam Smith, Milne-Edwards wrote that the body of all living beings, whether animal or plant, resembles a factory. Where the organs, comparable to workers, work incessantly to produce the phenomena that constitute the life of the individual, in more differentiated organisms, the functional labor could be apportioned between different instruments or systems. In 1858, Joseph Lister studied the cause of blood coagulation and inflammation that resulted after previous injuries and he later discovered and implemented antiseptics in the operating room, and as a result decreases death rate from surgery by a substantial amount. The Physiological Society was founded in London in 1876 as a dining club, the American Physiological Society is a nonprofit organization that was founded in 1887. The Society is, devoted to fostering education, scientific research, in 1891, Ivan Pavlov performed research on conditional reflexes that involved dogs saliva production in response to a plethora of sounds and visual stimuli
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Anatomy
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Anatomy is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is inherently tied to embryology, comparative anatomy, evolutionary biology, Human anatomy is one of the basic essential sciences of medicine. The discipline of anatomy is divided into macroscopic and microscopic anatomy, macroscopic anatomy, or gross anatomy, is the examination of an animals body parts using unaided eyesight. Gross anatomy also includes the branch of superficial anatomy, microscopic anatomy involves the use of optical instruments in the study of the tissues of various structures, known as histology, and also in the study of cells. The history of anatomy is characterized by an understanding of the functions of the organs. Anatomy and physiology, which study the structure and function of organisms and their parts, make a pair of related disciplines. Derived from the Greek ἀνατομή anatomē dissection, anatomy is the study of the structure of organisms including their systems, organs. It includes the appearance and position of the parts, the materials from which they are composed, their locations. Anatomy is quite distinct from physiology and biochemistry, which deal respectively with the functions of those parts, the discipline of anatomy can be subdivided into a number of branches including gross or macroscopic anatomy and microscopic anatomy. Gross anatomy is the study of large enough to be seen with the naked eye, and also includes superficial anatomy or surface anatomy. Microscopic anatomy is the study of structures on a scale, including histology. Anatomy can be studied using both invasive and non-invasive methods with the goal of obtaining information about the structure and organization of organs, angiography using X-rays or magnetic resonance angiography are methods to visualize blood vessels. The term anatomy is commonly taken to refer to human anatomy, however, substantially the same structures and tissues are found throughout the rest of the animal kingdom and the term also includes the anatomy of other animals. The term zootomy is also used to specifically refer to animals. The structure and tissues of plants are of a dissimilar nature, the kingdom Animalia or metazoa, contains multicellular organisms that are heterotrophic and motile. Most animals have bodies differentiated into separate tissues and these animals are known as eumetazoans. They have a digestive chamber, with one or two openings, the gametes are produced in multicellular sex organs, and the zygotes include a blastula stage in their embryonic development. Metazoans do not include the sponges, which have undifferentiated cells, unlike plant cells, animal cells have neither a cell wall nor chloroplasts
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Mathematics
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Mathematics is the study of topics such as quantity, structure, space, and change. There is a range of views among mathematicians and philosophers as to the exact scope, Mathematicians seek out patterns and use them to formulate new conjectures. Mathematicians resolve the truth or falsity of conjectures by mathematical proof, when mathematical structures are good models of real phenomena, then mathematical reasoning can provide insight or predictions about nature. Through the use of abstraction and logic, mathematics developed from counting, calculation, measurement, practical mathematics has been a human activity from as far back as written records exist. The research required to solve mathematical problems can take years or even centuries of sustained inquiry, rigorous arguments first appeared in Greek mathematics, most notably in Euclids Elements. Galileo Galilei said, The universe cannot be read until we have learned the language and it is written in mathematical language, and the letters are triangles, circles and other geometrical figures, without which means it is humanly impossible to comprehend a single word. Without these, one is wandering about in a dark labyrinth, carl Friedrich Gauss referred to mathematics as the Queen of the Sciences. Benjamin Peirce called mathematics the science that draws necessary conclusions, David Hilbert said of mathematics, We are not speaking here of arbitrariness in any sense. Mathematics is not like a game whose tasks are determined by arbitrarily stipulated rules, rather, it is a conceptual system possessing internal necessity that can only be so and by no means otherwise. Albert Einstein stated that as far as the laws of mathematics refer to reality, they are not certain, Mathematics is essential in many fields, including natural science, engineering, medicine, finance and the social sciences. Applied mathematics has led to entirely new mathematical disciplines, such as statistics, Mathematicians also engage in pure mathematics, or mathematics for its own sake, without having any application in mind. There is no clear line separating pure and applied mathematics, the history of mathematics can be seen as an ever-increasing series of abstractions. The earliest uses of mathematics were in trading, land measurement, painting and weaving patterns, in Babylonian mathematics elementary arithmetic first appears in the archaeological record. Numeracy pre-dated writing and numeral systems have many and diverse. Between 600 and 300 BC the Ancient Greeks began a study of mathematics in its own right with Greek mathematics. Mathematics has since been extended, and there has been a fruitful interaction between mathematics and science, to the benefit of both. Mathematical discoveries continue to be made today, the overwhelming majority of works in this ocean contain new mathematical theorems and their proofs. The word máthēma is derived from μανθάνω, while the modern Greek equivalent is μαθαίνω, in Greece, the word for mathematics came to have the narrower and more technical meaning mathematical study even in Classical times
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Leiden University Medical Center
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Leiden University Medical Center or LUMC is the university hospital affiliated with Leiden University, of which it forms the medical faculty. It is located in Leiden, Netherlands, LUMC is a modern university medical center for research, education and patient care. Its research practice ranges from pure fundamental medical research to applied clinical research, the hospital has clinical departments of all medical specialties, and acts as a tertiary referral centre for the northern part of the province of South Holland. Within LUMC different specialists work together around research themes, combining cross-border expertise may solve biomedical problems and bring answers not found when working in a stand-alone fashion. Education is seen as a joint responsibility of students and professors, enjoying studies and student life is also considered to be important. LUMC offers the following university courses, Bachelor and master in Medicine Bachelor and master in Biomedical Sciences Bachelor in Clinical Technology Master in Vitality, Master in Pharmacy Electives and exchange options for international students LUMC also offers continuing education and training for doctors, scientists and other healthcare professionals. Continuing education is organized by the departments Boerhaave nascholing and Educatie Zorgsector, in the very first teaching hospital in the Caeciliagasthuis in Leiden professors gave bedside lectures – for example, Herman Boerhaave, in the 18thcentury. Several times, patients and professors moved to larger and better furnished premises, at the time, the building did justice to nursing practices and operation techniques, but after a few decades it was already obsolete. More laboratory space was needed, and safer and more conditions for patients. The new hospital on Rijnsburgerweg, built in the early 1920s on the basis of the pavilion system, Medicine has changed and developed beyond recognition over the centuries. After World War II, fundamental research became an important task of Leiden University’s Faculty of Medicine. The Biomedical Science study programme is an expression of this, in patient care, high technology treatments have come in the place of admissions lasting weeks or months. The opening of two new buildings on 1 December 2006 was the fulfilment of a wish of long standing, the various buildings are linked by skyways and tunnels, thus symbolising the interrelationship of the core tasks. Universiteit Leiden Leiden Official website LUMC
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National Museum of Ethnology (Netherlands)
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The National Museum of Ethnology is a museum about ethnology in the Netherlands is located in the university city of Leiden. The institution which was at first called the Museum Japonicum and it was the first museum in Europe which was designed to demonstrate that collecting the artefacts of man could mean more than the mere accumulation of curiosities. From the very outset, this innovative institution incorporated at least four basic principles, collecting, scientific research, presentation to the public, van de Kasteele to collect Japanese objects for his collection. The resulting gift of about 5,000 objects became the heart the new museums holdings, Siebolds home in Leiden—and the objects he brought to Europe after eight years in Japan—was opened to the public in the early 1830s. The Dutch crown had previously purchased the smaller collections of Jan Cock Blomhoff in 1826 and this institution would later evolve into the National Museum of Ethnology. In 1843, Siebold also encouraged other Europeans to create ethnographic institutions similar to what was developing in Leiden, the collection today contains a large number of objects from Africa, China, Indonesia, Japan, Korea, Latin America, North America, Oceania, and Asia. As Opperhoofd for the Dutch East India Company at Dejima island in Nagasaki harbor from 1817 through 1823, despite the Japanese closed door policy for Westerners, he did transport his wife, Titia, and children to join him. Johannes Gerhard Frederik van Overmeer Fischer began as a clerk at Dejima and this material was brought back to the Netherlands in 1829. In 1833, he published Bijdrage tot de kennis van het Japansche rijk, further information relating to this material was published in Siebolds Nippon. His professional interest was drawn to implements used in the practice of traditional Japanese medicine. As of 2005, a museum located in one of Siebolds former houses. The Leiden plate is a Maya belt plaque and important historical artifact from Guatemala and it is depicted on the reverse of a one Guatemalan quetzal banknote. Tropenmuseum, Amsterdam Edo-Tokyo Museum National Museum of Ethnology, Japan The Virtual Collection of Masterpieces Alpen, Jan van, Oriental Medicine, An Illustrated Guide to the Asian Arts of Healing. Book Review, Titia, The First Western Woman in Japan by Rene P. Bersma, Pacific Affairs, Vol.76, Museum Studies, An Anthology of Contexts. ISBN 978-0-631-22830-1 Frederiks, Johannes Godefridus and F. Jos. van den Branden, Johannes Gerhard Frederik van Overmeer Fischer, Biographisch woordenboek der Noord- en Zuidnederlandsche letterkunde. Otterspeer, W. Leiden Oriental Connections, 1850-1940, Vol. V, ISBN 978-90-04-09022-4 Siebold, Philipp Franz von. Lettre sur lutilité des Musées Ethnographiques et sur limportance de leur création dans états européens qui posèdents des Colonies, rudolf Effert, Royal cabinets and auxiliary branches, origins of the National Museum of Ethnology, 1816-1883. ISBN 978-90-5789-159-5 Edo-Tokyo Museum exhibition catalog, a Very Unique Collection of Historical Significance, The Kapitan Collection from the Edo Period—The Dutch Fascination with Japan
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Convent
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A convent is either a community of priests, religious brothers or religious sisters, or the building used by the community, particularly in the Roman Catholic Church and in the Anglican Communion. The term derives via Old French from Latin conventus, perfect participle of the verb convenio, meaning to convene, the original reference was to the gathering of mendicants who spent much of their time travelling. Technically, a monastery or nunnery is a community of monastics, whereas a friary or convent is a community of mendicants, and a canonry a community of canons regular. The terms abbey and priory can be applied to both monasteries and canonries, an abbey is headed by an Abbot, and a priory is a dependent house headed by a Prior. In English usage since about the 19th century the term convent almost invariably refers to a community of women, in historical usage they are often interchangeable, with convent especially likely to be used for a friary. When applied to houses in Eastern Orthodoxy and Buddhism, English refers to all houses of male religious as monasteries. Christian monasticism Enclosed religious orders Herbermann, Charles, ed. Convent, carmelite Monastery of the Sacred Hearts —- an example of a modern-day convent Chisholm, Hugh, ed. Convent
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Saint Cecilia
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Saint Cecilia is the patroness of musicians. It is written that as the musicians played at her wedding she sang in her heart to the Lord and her feast day is celebrated in the Latin Catholic, Eastern Catholic, Anglican, and Eastern Orthodox churches on November 22. She is one of seven women, excluding the Blessed Virgin, while the details of her story appear to be fictional, her existence and martyrdom are considered a historical fact. She is said to have been beheaded with a sword, an early Roman Christian church, Santa Cecilia, was founded in the fourth century in the Trastevere section of Rome, reputedly on the site of the house in which she lived. A number of compositions are dedicated to her, and her feast day, November 22, became the occasion for concerts. St. Cecilia is one of the most famous of the Roman martyrs, according to Johann Peter Kirsch, while it is a pious romance, like so many others compiled in the fifth and sixth century, the existence of the martyrs, however, is a historical fact. The relation between St. Cecilia and Valerianus, Tiburtius, and Maximus, mentioned in the Acts of the Martyrs, has some historical foundation. Her feast day has been celebrated since about the fourth century, the research of Giovanni Battista de Rossi agrees with the statement of Venantius Fortunatus, Bishop of Poitiers, that she perished in Sicily under Emperor Marcus Aurelius between 176 and 180. According to the story, despite her vow of virginity, she was forced by her parents to marry a nobleman named Valerian. During the wedding, Cecilia sat apart singing to God in her heart, when Valerian asked to see the angel, Cecilia replied that he could if he would go to the third milestone on the Via Appia and be baptized by Pope Urban I. After following Cecilias advice, he saw the angel standing beside her, the martyrdom of Cecilia is said to have followed that of her husband Valerian and his brother at the hands of the prefect Turcius Almachius. The legend about Cecilia’s death says that after being three times on the neck with a sword, she lived for three days, and asked the pope to convert her home into a church. Cecilia was buried at the Catacombs of St. Callistus, in 1599, her body was found still incorrupt, seeming to be asleep. There is no mention of Cecilia in the Depositio Martyrum, but there is a record of an early Roman church founded by a lady of this name, the church of Santa Cecilia in Trastevere is reputedly built on the site of the house in which she lived. The original church was constructed in the century, during the ninth century. In 1599, while leading a renovation of the church, Cardinal Paolo Emilio Sfondrati had the remains, the name Cecilia was shared by all women of the Roman gens known as the Caecilii, whose name may be related to the root of caecus. Legends and hagiographies, mistaking it for a name, suggest fanciful etymologies. The first record of a festival in her honor was held at Évreux in Normandy in 1570
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Reformation
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The period is usually considered to have begun with the publication of the Ninety-five Theses by Luther in 1517 to the Thirty Years War and ended with the Peace of Westphalia in 1648. The Protestant position, however, would come to incorporate doctrinal changes such as sola scriptura, the initial movement within Germany diversified, and other reform impulses arose independently of Luther. The spread of Gutenbergs printing press provided the means for the dissemination of religious materials in the vernacular. The largest groups were the Lutherans and Calvinists, Lutheran churches were founded mostly in Germany, the Baltics and Scandinavia, while the Reformed ones were founded in Switzerland, Hungary, France, the Netherlands and Scotland. The new movement influenced the Church of England decisively after 1547 under Edward VI and Elizabeth I, there were also reformation movements throughout continental Europe known as the Radical Reformation, which gave rise to the Anabaptist, Moravian and other Pietistic movements. The Roman Catholic Church responded with a Counter-Reformation initiated by the Council of Trent, much work in battling Protestantism was done by the well-organised new order of the Jesuits. In general, Northern Europe, with the exception of most of Ireland, southern Europe remained Roman Catholic, while Central Europe was a site of a fierce conflict, culminating in the Thirty Years War, which left it devastated. The oldest Protestant churches, such as the Unitas Fratrum and Moravian Church, the later Protestant Churches generally date their doctrinal separation from the Roman Catholic Church to the 16th century. The Reformation began as an attempt to reform the Roman Catholic Church, by priests who opposed what they perceived as false doctrines and ecclesiastic malpractice. They especially objected to the teaching and the sale of indulgences, and the abuses thereof, and to simony, the reformers saw these practices as evidence of the systemic corruption of the Churchs hierarchy, which included the pope. Unrest due to the Great Schism of Western Christianity excited wars between princes, uprisings among the peasants, and widespread concern over corruption in the Church, New perspectives came from John Wycliffe at Oxford University and from Jan Hus at the Charles University in Prague. Hus rejected indulgences and adopted a doctrine of justification by grace through faith alone, the Roman Catholic Church officially concluded this debate at the Council of Constance by condemning Hus, who was executed by burning despite a promise of safe-conduct. Wycliffe was posthumously condemned as a heretic and his corpse exhumed and burned in 1428, the Council of Constance confirmed and strengthened the traditional medieval conception of church and empire. The council did not address the national tensions or the theological tensions stirred up during the century and could not prevent schism. Pope Sixtus IV established the practice of selling indulgences to be applied to the dead, Pope Alexander VI was one of the most controversial of the Renaissance popes. He was the father of seven children, including Lucrezia and Cesare Borgia, in response to papal corruption, particularly the sale of indulgences, Luther wrote The Ninety-Five Theses. The Reformation was born of Luthers dual declaration – first, the discovering of Jesus and salvation by faith alone, the Protestant reformers were unanimous in agreement and this understanding of prophecy furnished importance to their deeds. It was the point and the battle cry that made the Reformation nearly unassailable
30.
Gaper
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A gaper is a stone or wooden head, often depicting a Moor, on the front of a building in the Netherlands. It was used to indicate that the building is a pharmacy, the literal translation of gaper would be yawner, the figure is always displayed with an open mouth, sometimes with a pill resting on his tongue. This indicates that in fact he wasnt yawning, but opening his mouth to take medicine, the existing gapers in Amsterdam are almost all of Moorish appearance. This wasnt supposed to be the forefather of todays pharmacist, the apothecary would attend market days all over the country and his assistant would play the character of an ill man. After taking the pill, the assistant would all of a feel much better. Later, when pharmacists opened shops instead of travelling through the country, outside museum collections, fewer than 50 can be seen on buildings. Some have now lent their names to cafes, such as De Vergulde Gaper in Amsterdam
31.
Pharmacist
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Pharmacists, also known as chemists or druggists, are healthcare professionals who practice in pharmacy, the field of health sciences focusing on safe and effective medication use. A pharmacist is a member of the care team directly involved with patient care. This is mated to anatomy, physiology, and pathophysiology, Pharmacists interpret and communicate this specialized knowledge to patients, physicians, and other health care providers. Among other licensing requirements, different countries require pharmacists to hold either a Bachelor of Pharmacy, Master of Pharmacy, in most countries, the profession is subject to professional regulation. Depending on the scope of practice, pharmacists may contribute to prescribing and administering certain medications in some jurisdictions. Pharmacists may also practice in a variety of settings, including industry, wholesaling, research, academia, military. Historically, the role of pharmacists as a healthcare practitioner was to check. Pharmacists monitor the health and progress of patients to ensure the safe, Pharmacists may practice compounding, however, many medicines are now produced by pharmaceutical companies in a standard dosage and drug delivery form. One of the most important roles that pharmacists are currently taking on is one of pharmaceutical care, Pharmaceutical care involves taking direct responsibility for patients and their disease states, medications, and management of each to improve outcomes. Pharmacists are often the first point-of-contact for patients with health inquiries, thus pharmacists have a significant role in assessing medication management in patients, and in referring patients to physicians. In most countries, pharmacists must obtain a university degree at a school or related institution. In many contexts, students must first complete pre-professional coursework, followed by four years of professional academic studies to obtain a degree in pharmacy. Additional curriculum may cover diagnosis with emphasis on tests, disease state management, therapeutics. On graduation, pharmacists are licensed, either nationally or regionally, some may undergo further specialized training, such as in cardiology or oncology. Specialties include, The Australian Pharmacy Council is the independent accreditation agency for Australian pharmacists and it conducts examinations on behalf of the Pharmacy Board of Australia towards eligibility for registration. The Australian College of Pharmacy provides continuing education programs for pharmacists, wages for pharmacists in Australia appear to have stagnated. The award wages for a pharmacist is $812 a week, Pharmacist graduates are the lowest paid university graduates most years. Most pharmacists do earn above the wage, the average male pharmacist earns $65,000
32.
Herbalism
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Herbalism is the study of botany and use of plants intended for medicinal purposes or for supplementing a diet. Plants have been the basis for medical treatments through much of human history, modern medicine recognizes herbalism as a form of alternative medicine, as the practice of herbalism is not strictly based on evidence gathered using the scientific method. Modern medicine makes use of many plant-derived compounds as the basis for evidence-based pharmaceutical drugs, the scope of herbal medicine is sometimes extended to include fungal and bee products, as well as minerals, shells and certain animal parts. General practices include ancient methods of traditional Chinese medicine and Ayurveda, practitioners of herbalism or phytotherapy are referred to as herbalists or phytotherapists. Products used in herbalism may be called herbal medicines, botanicals, natural products, herbal remedies, herbal supplements. Archaeological evidence indicates that the use of plants dates back to the Paleolithic age. Written evidence of herbal remedies dates back over 5,000 years, to the Sumerians, a number of ancient cultures wrote about plants and their medical uses in books called herbals. In ancient Egypt, herbs are mentioned in Egyptian medical papyri, depicted in tomb illustrations, or on rare occasions found in medical jars containing trace amounts of herbs. Among the oldest, lengthiest, and most important medical papyri of ancient Egypt, the Ebers Papyrus dates from about 1550 BC, the earliest known Greek herbals come from Theophrastus of Eresos who in the 4th c. B. C. wrote in Greek Historia Plantarum, from Diocles of Carystus who wrote during the 3rd century B. C, only a few fragments of these works have survived intact, but from what remains scholars have noted a large amount of overlap with the Egyptian herbals. Seeds likely used for herbalism have been found in sites of Bronze Age China dating from the Shang Dynasty. Over a hundred of the 224 drugs mentioned in the Huangdi Neijing, herbs also commonly featured in the medicine of ancient India, where the principal treatment for diseases was diet. The World Health Organization estimates that 80 percent of the population of some Asian and African countries presently use herbal medicine for some aspect of health care. Pharmaceuticals are prohibitively expensive for most of the population, half of whom lived on less than $2 U. S. per day in 2002. In comparison, herbal medicines can be grown from seed or gathered from nature for little or no cost, many of the pharmaceuticals currently available to physicians have a long history of use as herbal remedies, including opium, aspirin, digitalis, and quinine. According to the World Health Organization, approximately 25% of modern drugs used in the United States have been derived from plants, at least 7,000 medical compounds in the modern pharmacopoeia are derived from plants. In a 2010 global survey of the most common 1000 plant-derived compounds, preclinical studies were reported for about one-half of the plant products, while 12% of the plants, although available in the Western market, had no substantial studies of their properties. Strong evidence was found that 5 were toxic or allergenic, so that their use ought to be discouraged or forbidden, according to Cancer Research UK, there is currently no strong evidence from studies in people that herbal remedies can treat, prevent or cure cancer
33.
Naturalis Biodiversity Center
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Naturalis Biodiversity Center is a national museum of natural history and a research center on biodiversity in Leiden, Netherlands. Although its current name and organization is relatively recent, its history can be traced back to the early 1800s and its collections contain approximately 37 million specimens, one of the largest natural history collections in the world. In late 2016 the center closed its building for renovations. Temporary exhibitions are open in the entrance building during the renovations. The beginnings of Naturalis go back to the creation of the National Museum of Natural History by King William I on August 9,1820, in 1878, the geological and mineralogical collections of the museum separated into two institutions. In 1986, it was determined that the institution should become a museum. The buildings reception area incorporated the 1657-1661 Pesthuis, designed by Huybert Corneliszoon van Duyvenvlucht, completed in 1998, it was opened on April 7,1998 by Queen Beatrix. The new building cost about €60 million, making it the second most expensive building in the Netherlands. The combined institute was opened as part of the ‘International Year of Biodiversity 2010’ by Ronald Plasterk. As of 2012 the name became the Naturalis Biodiversity Center, Naturalis has partnered with ETI Bioinformatics in support of the Catalogue of Life, and is working with the Global Biodiversity Information Facility. Funding is in place to support digitization of the massed collections, as of 2015, further renovation and expansion is planned, with a proposed design from Neutelings Riedijk Architecten to be completed in 2018. However, the Pesthuis will no longer be part of the complex, some parts of the collections are stored in a depot in the former museum building at the Raamsteeg in the city centre of Leiden. Rex in Town exhibition of Trix, a Tyrannosaurus skeleton, September 10,2016 to June,52017, Naturalis had an estimated 285,000 visitors and was the 15th most visited museum of the Netherlands in 2013. The museum had a number of 339,550 visitors in 2015. Naturalis, official website Naturalis extinct birds, 3D presentation Naturalis Biodiversity Center at Google Cultural Institute
34.
Surgeon
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In medicine, a surgeon is a doctor who performs operations. Surgeons may be physicians, podiatrists, dentists, or veterinarians, the first person to document a surgery was the 6th Century BC Indian physician-surgeon, Sushrutha. He is considered the greatest medieval surgeon to have appeared from the Islamic World and his greatest contribution to medicine is the Kitab al-Tasrif, a thirty-volume encyclopedia of medical practices. He was the first physician to describe an ectopic pregnancy, in Europe, surgery was mostly associated with barber-surgeons who also used their hair-cutting tools to undertake surgical procedures, often at the battlefield and also for their royal paymasters. In 1950, the Royal College of Surgeons of England in London began to offer surgeons a formal status via RCS membership. The distinction of Mr is also used by surgeons in the Republic of Ireland, Australia, Barbados, New Zealand, South Africa, Zimbabwe, in many English-speaking countries the military title of surgeon is applied to any medical practitioner, due to the historical evolution of the term. Some physicians who are general practitioners or specialists in medicine or emergency medicine may perform limited ranges of minor, common. Anesthesia often accompanies surgery, and anesthesiologists and nurse anesthetists may oversee this aspect of surgery, Surgeons assistant, surgical nurses, surgical technologists and operating department practitioners are trained professionals who support surgeons. Sushruta Abu al-Qasim al-Zahrawi Charles Kelman William Stewart Halsted Alfred Blalock C
35.
Guild
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A guild /ɡɪld/ is an association of artisans or merchants who control the practice of their craft in a particular town. The earliest types of guild were formed as confraternities of tradesmen and they were organized in a manner something between a professional association, trade union, a cartel, and a secret society. A lasting legacy of traditional guilds are the guildhalls constructed and used as meeting places, an important result of the guild framework was the emergence of universities at Bologna, Oxford and Paris, they originated as guilds of students as at Bologna, or of masters as at Paris. Usually the founders were free independent master craftsmen who hired apprentices, there were several types of guilds, including the two main categories of merchant guilds and craft guilds but also the frith guild and religious guild. In many cases became the governing body of a town. The Freedom of the City, effective from the Middle Ages until 1835, gave the right to trade, Trade guilds arose in the 14th century as craftsmen united to protect their common interest. The occasion for these oaths were drunken banquets held on December 26, gregory of Tours tells a miraculous tale of a builder whose art and techniques suddenly left him, but were restored by an apparition of the Virgin Mary in a dream. Michel Rouche remarks that the story speaks for the importance of practically transmitted journeymanship, in France, guilds were called corps de métiers. According to Viktor Ivanovich Rutenburg, Within the guild itself there was little division of labour. Thus, according to Étienne Boileaus Book of Handicrafts, by the century there were no less than 100 guilds in Paris. In Catalan towns, specially at Barcelona, guilds or gremis were a basic agent in the society, a shoemakers guild is recorded in 1208. In England, specifically in the City of London Corporation, more than 110 guilds, referred to as companies, survive today. Other groups, such as the Worshipful Company of Tax Advisers, have been formed far more recently, membership in a livery company is expected for individuals participating in the governance of The City, as the Lord Mayor and the Remembrancer. The guild system reached a state in Germany circa 1300 and held on in German cities into the 19th century. In the 15th century, Hamburg had 100 guilds, Cologne 80, the latest guilds to develop in Western Europe were the gremios of Spain, e. g. Valencia or Toledo. Not all city economies were controlled by guilds, some cities were free, in order to become a Master, a Journeyman would have to go on a three-year voyage called Journeyman years. The practice of the Journeyman years still exists in Germany and France, in Ghent, as in Florence, the woolen textile industry developed as a congeries of specialized guilds. The appearance of the European guilds was tied to the emergent money economy, before this time it was not possible to run a money-driven organization, as commodity money was the normal way of doing business
36.
Allegory
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As a literary device, an allegory is a metaphor whose vehicle may be a character, place or event, representing real-world issues and occurrences. Many ancient religions are based on astrological allegories, that is, allegories of the movement of the sun, in classical literature two of the best-known allegories are the Cave in Platos Republic and the story of the stomach and its members in the speech of Menenius Agrippa. One of the examples of allegory, Platos Allegory of the Cave. In this allegory, Plato describes a group of people who have lived chained in an all of their lives. The people watch shadows projected on the wall by things passing in front of a fire behind them and begin to ascribe forms to these shadows, using language to identify their world. He tries to tell the people in the cave of his discovery, also allegorical is Ezekiel 16 and 17, wherein the capture of that same vine by the mighty Eagle represents Israels exile to Rome. Allegory has an ability to freeze the temporality of a story, Mediaeval thinking accepted allegory as having a reality underlying any rhetorical or fictional uses. The allegory was as true as the facts of surface appearances, if, then, the Greeks or others say that they were not committed to the care of Peter and his successors, they necessarily confess that they are not of the sheep of Christ. This text also demonstrates the frequent use of allegory in religious texts during the Mediaeval Period, following the tradition, since meaningful stories are nearly always applicable to larger issues, allegories may be read into many stories which the author may not have recognised. This is allegoresis, or the act of reading a story as an allegory. S, lewis and A Kingdom Far and Clear, The Complete Swan Lake Trilogy by Mark Helprin. The story of the apple falling onto Isaac Newtons head is another famous allegory and it simplified the idea of gravity by depicting a simple way it was supposedly discovered. It also made the scientific revelation well known by condensing the theory into a short tale. According to Henry Littlefields 1964 article, L. Yet, George MacDonald emphasised in 1893 that, A fairy tale is not an allegory, I much prefer history – true or feigned– with its varied applicability to the thought and experience of readers. I think that many confuse applicability with allegory, but the one resides in the freedom of the reader, and this further reinforces the idea of forced allegoresis, as allegory is often a matter of interpretation and only sometimes of original artistic intention. Like allegorical stories, allegorical poetry has two meanings – a literal meaning and a symbolic meaning, some unique specimens of allegory can be found in the following works, Edmund Spenser – The Faerie Queene, The several knights in the poem actually stand for several virtues. Nathaniel Hawthorne – Young Goodman Brown, The Devils Staff symbolises defiance of God, the characters names, such as Goodman and Faith, ironically serve as paradox in the conclusion of the story. Nathaniel Hawthorne – The Scarlet Letter, The scarlet letter symbolises many things, the characters, while developed with interiority, are allegorical in that they represent ways of seeing the world. George Orwell – Animal Farm, The pigs stand for political figures of the Russian Revolution, lászló Krasznahorkai - The Melancholy of Resistance and the film Werckmeister Harmonies, It uses a circus to describe an occupying dysfunctional government
37.
Devil
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The Devil is, according to Christianity, the primary opponent of God. Islam identifies the Devil with all those who oppose Allah, some non-Abrahamic religions contain figures similar to the Devil, such as the Buddhist demon Mara and the Zoroastrian spirit Angra Mainyu. The Modern English word devil descends from the Middle English devel, from Old English dēofol, that in turn represents an early Germanic borrowing of Latin diabolus. This in turn was borrowed from Ancient Greek Greek, διάβολος, slanderer, from Greek, διαβάλλειν to slander, διά- across, through + βάλλειν to hurl, probably akin to the Sanskrit gurate he lifts up. In the New Testament, Satan occurs more than 30 times in passages alongside diábolos, in mainstream Judaism there is no concept of a devil as in mainstream Christianity or Islam. Texts make no direct link between the serpent that tempts Eve in the Garden of Eden in Genesis and the references to Satan are in Zechariah. For the Hasidim of the century, ha-satan was Baal Davar. In the Book of Wisdom, the devil is represented as the one who brought death into the world, a similar story is found in 1 Enoch, however, in that book, the leader of the Grigori is called Semjâzâ. In the apocryphal literature, Satan rules over a host of angels, mastema, who induced God to test Abraham through the sacrifice of Isaac, is identical with Satan in both name and nature. The Book of Enoch contains references to Sathariel, thought also to be Sataniel and Satanel, the similar spellings mirror that of his angelic brethren Michael, Raphael, Uriel and Gabriel, previous to his expulsion from Heaven. In mainstream Christianity the devil is usually referred to as Satan, some modern Christians consider the devil to be an angel who, along with one-third of the angelic host rebelled against God and has consequently been condemned to the Lake of Fire. He is described as hating all humanity, opposing God, spreading lies, other modern Christians consider the devil in the Bible to refer figuratively to human sin and temptation and to any immoral human system. Satan is often identified as the serpent who convinced Eve to eat the fruit, thus. He is also identified as the dragon in the Book of Revelation, beelzebub is originally the name of a Philistine god but is also used in the New Testament as a synonym for Satan. A corrupted version, Belzeboub, appears in The Divine Comedy, in Islam the Devil is referred to as Iblis or sometimes the Shaytan. Etymologically, Iblis means the desperate in Arabic, thus, the name Iblis can be seen as a sobriquet given to Shaitan after falling from Grace. The primary characteristic of the Devil, besides hubris, is that he has no other than the power to cast evil suggestions into the hearts of men and women. He was of the jinn and departed from the command of his Lord, then will you take him and his descendants as allies other than Me while they are enemies to you
38.
Saints Cosmas and Damian
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Saints Cosmas and Damian were reputed twin brothers, physicians, and early Christian martyrs. They practiced their profession in the seaport of Aegeae, then in the Roman province of Syria, accepting no payment for their services led to them being named Anargyroi, it has been said that, by this, they attracted many to the Christian faith. Nothing is known of their lives except that they suffered martyrdom in Syria during the persecution of the Emperor Diocletian, according to Christian traditions, the twin brothers were born in Arabia and became skilled doctors. During the persecution under Diocletian, Cosmas and Damian were arrested by order of the Prefect of Cilicia, one Lysias who is otherwise unknown, who ordered them under torture to recant. However, according to legend they stayed true to their faith, enduring being hung on a cross, stoned and shot by arrows, anthimus, Leontius and Euprepius, their younger brothers, who were inseparable from them throughout life, shared in their martyrdom. As early as the 4th century, churches dedicated to the saints were established at Jerusalem, in Egypt. Devotion to the two saints spread rapidly in both East and West, theodoret records the division of their reputed relics. Their relics, deemed miraculous, were buried in the city of Cyrrus in Syria, at Rome Pope Felix IV rededicated the Library of Peace as a basilica of Santi Cosma e Damiano in the Forum of Vespasian in their honour. The church is much rebuilt but still famed for its sixth-century mosaics illustrating the saints, what are said to be their skulls are venerated in the convent of the Clares in Madrid, where they have been since 1581, the gift of Maria, daughter of Emperor Charles V. They had previously removed from Rome to Bremen in the tenth century. Other skulls said to be theirs were discovered in 1334 by Burchard Grelle and he personally miraculously retrieved the relics of the holy physicians Cosmas and Damian, which were allegedly immured and forgotten in the choir of the Bremen Cathedral. In celebration of the retrieval Archbishop and Chapter arranged a feast at Pentecost 1335, Grelle claimed the relics were those Archbishop Adaldag brought from Rome in 965. The cathedral master-builder Johann Hemeling made a shrine for the relics, the shrine, made from carved oak wood covered with gilt and rolled silver is considered an important mediaeval gold work. In 1649 Bremens Chapter, Lutheran by this time, sold the shrine without the heads to Maximilian I of Bavaria, the two heads remained in Bremen and came into the possession of the small Roman Catholic community. They were shown from 1934 to 1968 in the Church of St. Johann, the shrine is now shown in the Jesuit church of St Michael in Munich. At least since 1413 another supposed pair of skulls of the saints has been stored in St Stephenss Cathedral in Vienna, in Canada it has been moved to Sept.25. Sts Cosmas and Damian are regarded as the patrons of physicians and surgeons and are represented with medical emblems. The ritual consists of first offering the food to seven children that are no older than seven years old and then having them feast while sitting on the floor, only after all children have finished can the guests enjoy the food that is being offered
39.
Herb
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In general use, herbs are any plants used for food, flavoring, medicine, or fragrances for their savory or aromatic properties. Culinary use typically distinguishes herbs from spices, Herbs refers to the leafy green or flowering parts of a plant, while spices are produced from other parts of the plant, including seeds, berries, bark, roots and fruits. In botanical English, the herb is also used as a synonym of herbaceous plant. Herbs have a variety of uses including culinary, medicinal, and in some cases, general usage of the term herb differs between culinary herbs and medicinal herbs. In medicinal or spiritual use any of the parts of the plant might be considered herbs, including leaves, roots, flowers, seeds, root bark, inner bark, resin and pericarp. The word herb is pronounced /ˈhɜːrb/ in the UK, but /ˈɜːrb/ is common among North American speakers, as far back as 5000 BCE, Sumerians used herbs in medicine. Ancient Egyptians used fennel, coriander and thyme around 1555 BCE, in ancient Greece, in 162 CE, a physician by the name of Galen was known for concocting complicated herbal remedies that contained up to 100 ingredients. Culinary herbs are distinguished from vegetables in that, like spices, they are used in small amounts, Herbs can be perennials such as thyme or lavender, biennials such as parsley, or annuals like basil. Perennial herbs can be such as rosemary, Rosmarinus officinalis, or trees such as bay laurel, Laurus nobilis – this contrasts with botanical herbs. Some plants are used as herbs and spices, such as dill weed and dill seed or coriander leaves and seeds. Also, there are some such as those in the mint family that are used for both culinary and medicinal purposes. Some plants contain phytochemicals that have effects on the body, there may be some effects when consumed in the small levels that typify culinary spicing, and some herbs are toxic in larger quantities. For instance, some types of herbal extract, such as the extract of St. Johns-wort or of kava can be used for purposes to relieve depression. However, large amounts of these herbs may lead to toxic overload that may involve complications, some of a serious nature, Herbs have long been used as the basis of traditional Chinese herbal medicine, with usage dating as far back as the first century CE and far before. In India, the Ayurveda medicinal system is based on herbs, medicinal use of herbs in Western cultures has its roots in the Hippocratic elemental healing system, based on a quaternary elemental healing metaphor. Famous herbalist of the Western tradition include Avicenna, Galen, Paracelsus, Culpepper, the indigenous peoples of Australia developed herbal medicine based on plants that were readily available to them. The isolation of the people meant the remedies developed were for far less serious diseases. Herbs such as mint, wattle and eucalyptus were used for coughs, diarrhea, fever
40.
Renaissance
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The Renaissance was a period in European history, from the 14th to the 17th century, regarded as the cultural bridge between the Middle Ages and modern history. It started as a movement in Italy in the Late Medieval period and later spread to the rest of Europe. This new thinking became manifest in art, architecture, politics, science, Early examples were the development of perspective in oil painting and the recycled knowledge of how to make concrete. Although the invention of movable type sped the dissemination of ideas from the later 15th century. In politics, the Renaissance contributed to the development of the customs and conventions of diplomacy, the Renaissance began in Florence, in the 14th century. Other major centres were northern Italian city-states such as Venice, Genoa, Milan, Bologna, the word Renaissance, literally meaning Rebirth in French, first appeared in English in the 1830s. The word also occurs in Jules Michelets 1855 work, Histoire de France, the word Renaissance has also been extended to other historical and cultural movements, such as the Carolingian Renaissance and the Renaissance of the 12th century. The Renaissance was a movement that profoundly affected European intellectual life in the early modern period. Renaissance scholars employed the humanist method in study, and searched for realism, however, a subtle shift took place in the way that intellectuals approached religion that was reflected in many other areas of cultural life. In addition, many Greek Christian works, including the Greek New Testament, were back from Byzantium to Western Europe. Political philosophers, most famously Niccolò Machiavelli, sought to describe life as it really was. Others see more competition between artists and polymaths such as Brunelleschi, Ghiberti, Donatello, and Masaccio for artistic commissions as sparking the creativity of the Renaissance. Yet it remains much debated why the Renaissance began in Italy, accordingly, several theories have been put forward to explain its origins. During the Renaissance, money and art went hand in hand, Artists depended entirely on patrons while the patrons needed money to foster artistic talent. Wealth was brought to Italy in the 14th, 15th, and 16th centuries by expanding trade into Asia, silver mining in Tyrol increased the flow of money. Luxuries from the Eastern world, brought home during the Crusades, increased the prosperity of Genoa, unlike with Latin texts, which had been preserved and studied in Western Europe since late antiquity, the study of ancient Greek texts was very limited in medieval Western Europe. One of the greatest achievements of Renaissance scholars was to bring this entire class of Greek cultural works back into Western Europe for the first time since late antiquity, Arab logicians had inherited Greek ideas after they had invaded and conquered Egypt and the Levant. Their translations and commentaries on these ideas worked their way through the Arab West into Spain and Sicily and this work of translation from Islamic culture, though largely unplanned and disorganized, constituted one of the greatest transmissions of ideas in history
41.
Medicinal jar
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A Medicinal jar or drug jar is a jar used to contain medicine. Medicinal jars used to be employed massively in apothecary shops in hospitals, Medicinal jars are an important category of the famous Dutch and English porcelain known as Delftware. A famous type of drug jar known as Albarello was derived from Islamic wares
42.
Christiaan Huygens
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Christiaan Huygens, FRS was a prominent Dutch mathematician and scientist. He is known particularly as an astronomer, physicist, probabilist and horologist, Huygens was a leading scientist of his time. His work included early telescopic studies of the rings of Saturn and the discovery of its moon Titan and he published major studies of mechanics and optics, and pioneered work on games of chance. Christiaan Huygens was born on 14 April 1629 in The Hague, into a rich and influential Dutch family, Christiaan was named after his paternal grandfather. His mother was Suzanna van Baerle and she died in 1637, shortly after the birth of Huygens sister. The couple had five children, Constantijn, Christiaan, Lodewijk, Philips, Constantijn Huygens was a diplomat and advisor to the House of Orange, and also a poet and musician. His friends included Galileo Galilei, Marin Mersenne and René Descartes, Huygens was educated at home until turning sixteen years old. He liked to play with miniatures of mills and other machines and his father gave him a liberal education, he studied languages and music, history and geography, mathematics, logic and rhetoric, but also dancing, fencing and horse riding. In 1644 Huygens had as his mathematical tutor Jan Jansz de Jonge Stampioen, Descartes was impressed by his skills in geometry. His father sent Huygens to study law and mathematics at the University of Leiden, Frans van Schooten was an academic at Leiden from 1646, and also a private tutor to Huygens and his elder brother, replacing Stampioen on the advice of Descartes. Van Schooten brought his mathematical education up to date, in introducing him to the work of Fermat on differential geometry. Constantijn Huygens was closely involved in the new College, which lasted only to 1669, Christiaan Huygens lived at the home of the jurist Johann Henryk Dauber, and had mathematics classes with the English lecturer John Pell. He completed his studies in August 1649 and he then had a stint as a diplomat on a mission with Henry, Duke of Nassau. It took him to Bentheim, then Flensburg and he took off for Denmark, visited Copenhagen and Helsingør, and hoped to cross the Øresund to visit Descartes in Stockholm. While his father Constantijn had wished his son Christiaan to be a diplomat, in political terms, the First Stadtholderless Period that began in 1650 meant that the House of Orange was not in power, removing Constantijns influence. Further, he realised that his son had no interest in such a career, Huygens generally wrote in French or Latin. While still a student at Leiden he began a correspondence with the intelligencer Mersenne. Mersenne wrote to Constantijn on his sons talent for mathematics, the letters show the early interests of Huygens in mathematics
43.
Willem 's Gravesande
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Willem Jacob s Gravesande was a Dutch mathematician and natural philosopher, chiefly remembered for developing experimental demonstrations of the laws of classical mechanics. As professor of mathematics, astronomy, and philosophy at Leiden University, born in s-Hertogenbosch, s Gravesande studied law at Leiden University, where he defended a thesis on suicide and earned a doctorate in 1707. He then practiced law in The Hague while also participating in intellectual discussions and his Essai de perspective, published in 1711, was praised by the influential Swiss mathematician Johann Bernoulli. In The Hague, s Gravesande also helped to establish the Journal littéraire, in 1715, s Gravesande visited London as part of a Dutch delegation sent to welcome the Hanoverian succession in Great Britain. In London, s Gravesande met both King George I and Isaac Newton, and was elected a Fellow of the Royal Society, in 1717 he became professor of mathematics and astronomy in Leiden. From that position, he was instrumental in introducing Newtons work to the Netherlands and he also obtained the chairs of civil and military architecture in 1730 and philosophy in 1734. As a philosopher, he opposed fatalists like Hobbes and Spinoza, S Gravesande was married to Anna Sacrelaire in 1720. They had two sons, both of whom died in adolescence, in 1724, Peter the Great offered s Gravesande a position in the new Imperial Saint Petersburg Academy of Sciences. In 1737 he received an offer from Frederick the Great to join the Prussian Academy of Sciences in Berlin and he declined both offers, opting to remain in Leiden. Gravesandes main scientific work is Physices elementa mathematica, experimentis confirmata, sive introductio ad philosophiam Newtonianam, in that book, he laid the foundations for the teaching of Newtonian mechanics through experimental demonstrations. He presented his work before audiences that included, Voltaire and Albrecht von Haller, S Gravesandes book was soon translated into English by John Theophilus Desaguliers, curator of experiments for the Royal Society. In 1721, s Gravesande became involved in a controversy over whether the German inventor Johann Bessler. S Gravesande at first argued for the feasibility of perpetual motion based on the conservation of the scalar quantity mv, however, in 1722 he published the results of a series of experiments in which brass balls were dropped from varying heights onto a soft clay surface. Similar views were defended at the time by Gottfried Wilhelm Leibniz, Johann Bernoulli, and others, russian Tsar Peter the Great was interested in Besslers wheel and sought s Gravesandes advice on the subject. S Gravesande communicated his results on the impact of falling weights to Émilie du Châtelet, similar observations were published independently by Giovanni Poleni. S Gravesande is also remembered for his invention of an experiment demonstrating thermal expansion. This is known today as s Gravesandes experiment or s Gravesandes ring, the apparatus consists of a small metal ball on a chain or handle, and a metal ring on a stand. The ring is just big enough so that when the ring and ball are at the same temperature, the ball fits through the ring
