The National Medal of Science is an honor bestowed by the President of the United States to individuals in science and engineering who have made important contributions to the advancement of knowledge in the fields of behavioral and social sciences, biology, chemistry, engineering, mathematics and physics. The twelve member presidential Committee on the National Medal of Science is responsible for selecting award recipients and is administered by the National Science Foundation (NSF).

Theodore von Kármán, was a Hungarian-American mathematician, aerospace engineer, and physicist who worked in aeronautics and astronautics. He was responsible for crucial advances in aerodynamics characterizing supersonic and hypersonic airflow. The human-defined threshold of outer space is named the "Kármán line" in recognition of his work. Kármán is regarded as an outstanding aerodynamic theoretician of the 20th century.