New Mexico's 1st congressional district of the United States House of Representatives serves the central area of New Mexico, including most of Bernalillo County, all of Torrance County, and parts of Sandoval, Santa Fe and Valencia counties. It includes almost three-fourths of Albuquerque. The district has a notable Native American presence, encompassing several pueblos including the Pueblo of Laguna and Sandia Pueblo, and the Tohajiilee Navajo Reservation outside Albuquerque. The seat is currently represented by Democrat Melanie Stansbury. With a Cook Partisan Voting Index rating of D+5, it is the most Democratic district in New Mexico, a state with an all-Democratic congressional delegation.

Bernalillo County is the most populous county in the U.S. state of New Mexico. As of the 2020 census, the population was 676,444. The county seat, Albuquerque, is the most populous city in New Mexico.