New Mexico State Road 528 (NM 528) is a 15.355-mile-long (24.711 km) state highway in Sandoval County and Bernalillo County, New Mexico. NM 528 is signed as Alameda Blvd. In Rio Rancho, the road is also known as Pat D'Arco Highway, named after former mayor of Rio Rancho Pat D'Arco. It is an L-shaped route signed north-south in Sandoval County and east-west in Bernalillo County.

Interstate 25 (I-25) in the US state of New Mexico follows the north–south corridor through Albuquerque and Santa Fe. It replaced U.S. Route 85 (US 85), which is no longer signed, but still exists in route logs sharing most of the I-25 alignment. I-25 starts in New Mexico at an interchange with I-10 in Las Cruces and extends roughly 460 miles (740 km) before reaching Colorado. I-25 passes through principally rural land through central New Mexico and passes through or near the cities of Las Cruces, Truth or Consequences, Socorro, Belen, Albuquerque, Santa Fe, Las Vegas, and Raton.