The Newhall Pass interchange is a highway interchange at Newhall Pass in Southern California, United States. It is south of the city of Santa Clarita and north of the Los Angeles neighborhoods of Granada Hills and Sylmar. It connects Interstate 5 with California State Route 14. It is officially named in the memory of Los Angeles Police officer Clarence Wayne Dean, who was killed when he was unable to stop before going over a collapsed section of the interchange immediately following the 1994 Northridge earthquake.

Newhall Pass is a low mountain pass in Los Angeles County, California. Historically called Fremont Pass and San Fernando Pass, with Beale's Cut, it separates the Santa Susana Mountains from the San Gabriel Mountains. Although the pass was visited in August 1769 by Catalan explorer Gaspar de Portolá, it eventually was named for Henry Newhall, a significant businessman in the area during the 19th century.