Nicole Marie Passonno Stott is an American engineer and a retired NASA astronaut. She served as a flight engineer on ISS Expedition 20 and Expedition 21 and was a mission specialist on STS-128 and STS-133. After 27 years of working at NASA, the space agency announced her retirement effective June 1, 2015. She is married to Christopher Stott, a Manx-born American space entrepreneur.

Expedition 20 was the 20th long-duration flight to the International Space Station. The expedition marked the first time a six-member crew inhabited the station. Because each Soyuz-TMA spacecraft could hold only three people, two separate launches were necessary: Soyuz TMA-14 launched on 26 March 2009, and Soyuz TMA-15 followed on 27 May 2009.