Nitromethane, sometimes shortened to simply "nitro", is an organic compound with the chemical formula CH3NO2. It is the simplest organic nitro compound. It is a polar liquid commonly used as a solvent in a variety of industrial applications such as in extractions, as a reaction medium, and as a cleaning solvent. As an intermediate in organic synthesis, it is used widely in the manufacture of pesticides, explosives, fibers, and coatings. Nitromethane is used as a fuel additive in various motorsports and hobbies, e.g. Top Fuel drag racing and miniature internal combustion engines in radio control, control line and free flight model aircraft.

Top Fuel is a type of drag racing whose dragsters are the quickest accelerating racing cars in the world and the fastest sanctioned category of drag racing, with the fastest competitors reaching speeds of 338 miles per hour (544.0 km/h) and finishing the 1,000 foot (304.8 m) runs in 3.62 seconds.