Nkosazana Clarice Dlamini-Zuma, sometimes referred to by her initials NDZ, is a South African politician, medical doctor and former anti-apartheid activist. A longstanding member of the African National Congress (ANC), she currently serves as Minister in the Presidency responsible for Women, Youth and Persons with Disabilities and is the Chancellor of the University of Limpopo.

The 52nd National Conference of the African National Congress (ANC) was held in Polokwane, Limpopo, from 16 to 20 December 2007. At the conference, Jacob Zuma and his supporters were elected to the party's top leadership and National Executive Committee (NEC), dealing a significant defeat to national President Thabo Mbeki, who had sought a third term in the ANC presidency. The conference was a precursor to the general election of 2009, which the ANC was extremely likely to win and which did indeed lead to Zuma's ascension to the presidency of South Africa. Mbeki was prohibited from serving a third term as national President but, if re-elected ANC President, could likely have leveraged that office to select his successor.