In April 2022, a no-confidence motion against Imran Khan led to his removal as the prime minister of Pakistan. Based largely on the Westminster system of legislature, the prime minister commands confidence of the majority of the lower house of Parliament, the National Assembly of Pakistan, under clause (2A) of Article 91 of the Constitution. Numerous opposition parties joined forces to file the motion of no confidence against Imran Khan in the National Assembly. It ultimately led to the removal of Khan from office as a majority passed the motion in the Lower House.

A motion or vote of no confidence is a formal expression by a deliberative body as to whether an officeholder is deemed fit to continue to occupy their office. The no-confidence vote is a defining feature of parliamentary democracy which allows the elected parliament to either affirm their support or force the ousting of the cabinet. Systems differ in whether such a motion may be directed against the prime minister only or against individual cabinet ministers.