The North Wessex Downs National Landscape is located in the English counties of Berkshire, Hampshire, Oxfordshire and Wiltshire. The name North Wessex Downs is not a traditional one, the area covered being better known by various overlapping local names, including the Berkshire Downs, the North Hampshire Downs, the White Horse Hills, the Lambourn Downs, the Marlborough Downs, the Vale of Pewsey and Savernake Forest.

Oxfordshire is a ceremonial county in South East England. The county is bordered by Northamptonshire and Warwickshire to the north, Buckinghamshire to the east, Berkshire to the south, and Wiltshire and Gloucestershire to the west. The city of Oxford is the largest settlement and county town.