The nuclear weapons debate refers to the controversies surrounding the threat, use and stockpiling of nuclear weapons. Even before the first nuclear weapons had been developed, scientists involved with the Manhattan Project were divided over the use of the weapon. The only time nuclear weapons have been used in warfare was during the final stages of World War II when USAAF B-29 Superfortress bombers dropped atomic bombs on the Japanese cities of Hiroshima and Nagasaki in early August 1945. The role of the bombings in Japan's surrender and the U.S.'s ethical justification for them have been the subject of scholarly and popular debate for decades.

The anti-nuclear movement is a social movement that opposes various nuclear technologies. Some direct action groups, environmental movements, and professional organisations have identified themselves with the movement at the local, national, or international level. Major anti-nuclear groups include Campaign for Nuclear Disarmament, Friends of the Earth, Greenpeace, International Physicians for the Prevention of Nuclear War, Peace Action, Seneca Women's Encampment for a Future of Peace and Justice and the Nuclear Information and Resource Service. The initial objective of the movement was nuclear disarmament, though since the late 1960s opposition has included the use of nuclear power. Many anti-nuclear groups oppose both nuclear power and nuclear weapons. The formation of green parties in the 1970s and 1980s was often a direct result of anti-nuclear politics.