The Okavango River, is a river in southwest Africa. It is known by this name in Botswana, and as Cubango in Angola, and Kavango in Namibia. It is the fourth-longest river system in southern Africa, running southeastward for 1,600 km (1,000 mi). It begins at an elevation of 1,300 metres (4,300 ft) in the sandy highlands of Angola. Farther south, it forms part of the border between Angola and Namibia, and then flows into Botswana. The Okavango does not have an outlet to the sea. Instead, it discharges into the Okavango Delta or Okavango Alluvial Fan, in an endorheic basin in the Kalahari Desert. The Cuito River is a major tributary.

Lake Makgadikgadi was a paleolake that existed in what is now the Kalahari Desert in Botswana from 2,000,000 years BP to 10,000 years BP. It may have once covered an area of from 80,000 to 275,000 km2 and was 30 metres (98 ft) deep. The Okavango, Upper Zambezi, and Cuando rivers once all emptied into the lake. Its remains are seen in the Makgadikgadi salt pans, one of the largest salt pans in the world.