The Oldsmobile 88 is a full-size car that was sold and produced by Oldsmobile from 1949 until 1999. From 1950 until 1974, the 88 was the division's most profitable line, particularly the entry level models such as the 88 and Dynamic 88. The 88 series was also an image leader for Oldsmobile, particularly in the early years (1949–51), when it was one of the best performing automobiles, thanks to its relatively small size, light weight, and advanced overhead-valve high-compression V8 engine. This engine, originally designed for the larger C-bodied and more luxurious 98 series, also replaced the straight-8 on the smaller B-bodied 78. With the large, high performance V8, the Oldsmobile 88 is considered by some to be the first muscle car, although this title is disputed.

Oldsmobile was a brand of American automobiles, produced for most of its existence by General Motors. Originally established as "Olds Motor Vehicle Company" by Ransom E. Olds in 1897, it produced over 35 million vehicles, including at least 14 million built at its Lansing, Michigan factory alone.