1.
Kyoto
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Kyoto is a city located in the central part of the island of Honshu, Japan. It has a close to 1.5 million. Kyoto is also known as the thousand-year capital, in Japanese, the city has been called Kyō, Miyako, or Kyō no Miyako. In the 11th century, the city was renamed Kyoto, after the Chinese word for capital city, after the city of Edo was renamed Tokyo in 1868, and the seat of the Emperor was transferred there, Kyoto was known for a short time as Saikyō. Obsolete spellings for the name include Kioto, Miaco and Meaco. Another term commonly used to refer to the city in the period was Keishi. His last choice for the site was the village of Uda, the new city, Heian-kyō, a scaled replica of the then Tang capital Changan, became the seat of Japans imperial court in 794, beginning the Heian period of Japanese history. The city suffered destruction in the Ōnin War of 1467–1477. Battles between samurai factions spilled into the streets, and came to involve the court nobility and religious factions as well, nobles mansions were transformed into fortresses, deep trenches dug throughout the city for defense and as firebreaks, and numerous buildings burned. The city has not seen such widespread destruction since, Hideyoshi also built earthwork walls called odoi encircling the city. Teramachi Street in central Kyoto is a Buddhist temple quarter where Hideyoshi gathered temples in the city, throughout the Edo period, the economy of the city flourished as one of three major cities in Japan, the others being Osaka and Edo. The Hamaguri rebellion of 1864 burnt down 28,000 houses in the city, the modern city of Kyoto was formed on April 1,1889. The construction of Lake Biwa Canal in 1890 is one taken to revive the city. The population of the city exceeded one million in 1932, stimson, Secretary of War in the Roosevelt and Truman administrations, the city was removed from the list of targets and replaced by Nagasaki. The city was spared from conventional bombing as well, although small-scale air raids did result in casualties. As a result, the Imperial City of Kyoto is one of the few Japanese cities that still have an abundance of prewar buildings, however, modernization is continually breaking down the traditional Kyoto in favor of newer architecture, such as the Kyōto Station complex. Kyoto became a city designated by government ordinance on September 1,1956, in 1997, Kyoto hosted the conference that resulted in the protocol on greenhouse gas emissions that bears the citys name. Kyoto is located in a valley, part of the Yamashiro Basin, in the part of the mountainous region known as the Tamba highlands
2.
Japan
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Japan is a sovereign island nation in Eastern Asia. Located in the Pacific Ocean, it lies off the eastern coast of the Asia Mainland and stretches from the Sea of Okhotsk in the north to the East China Sea, the kanji that make up Japans name mean sun origin. 日 can be read as ni and means sun while 本 can be read as hon, or pon, Japan is often referred to by the famous epithet Land of the Rising Sun in reference to its Japanese name. Japan is an archipelago consisting of about 6,852 islands. The four largest are Honshu, Hokkaido, Kyushu and Shikoku, the country is divided into 47 prefectures in eight regions. Hokkaido being the northernmost prefecture and Okinawa being the southernmost one, the population of 127 million is the worlds tenth largest. Japanese people make up 98. 5% of Japans total population, approximately 9.1 million people live in the city of Tokyo, the capital of Japan. Archaeological research indicates that Japan was inhabited as early as the Upper Paleolithic period, the first written mention of Japan is in Chinese history texts from the 1st century AD. Influence from other regions, mainly China, followed by periods of isolation, from the 12th century until 1868, Japan was ruled by successive feudal military shoguns who ruled in the name of the Emperor. Japan entered into a period of isolation in the early 17th century. The Second Sino-Japanese War of 1937 expanded into part of World War II in 1941, which came to an end in 1945 following the bombings of Hiroshima and Nagasaki. Japan is a member of the UN, the OECD, the G7, the G8, the country has the worlds third-largest economy by nominal GDP and the worlds fourth-largest economy by purchasing power parity. It is also the worlds fourth-largest exporter and fourth-largest importer, although Japan has officially renounced its right to declare war, it maintains a modern military with the worlds eighth-largest military budget, used for self-defense and peacekeeping roles. Japan is a country with a very high standard of living. Its population enjoys the highest life expectancy and the third lowest infant mortality rate in the world, in ancient China, Japan was called Wo 倭. It was mentioned in the third century Chinese historical text Records of the Three Kingdoms in the section for the Wei kingdom, Wa became disliked because it has the connotation of the character 矮, meaning dwarf. The 倭 kanji has been replaced with the homophone Wa, meaning harmony, the Japanese word for Japan is 日本, which is pronounced Nippon or Nihon and literally means the origin of the sun. The earliest record of the name Nihon appears in the Chinese historical records of the Tang dynasty, at the start of the seventh century, a delegation from Japan introduced their country as Nihon
3.
Tokyo Stock Exchange
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The Tokyo Stock Exchange, which is called Tōshō or TSE/TYO for short, is a stock exchange located in Tokyo, Japan. It is the fourth largest stock exchange in the world by market capitalization of its listed companies. It had 2,292 listed companies with a market capitalization of US$4.09 trillion as of April 2015. In July 2012 a planned merger with the Osaka Securities Exchange was approved by the Japan Fair Trade Commission, the resulting entity, the Japan Exchange Group, was launched on January 1,2013. The TSE is incorporated as a kabushiki gaisha with nine directors, four auditors and its headquarters are located at 2-1 Nihonbashi-Kabutochō, Chūō, Tokyo, or Kabuto-chō, which is the largest financial district in Japan. Its operating hours are from 8,00 to 11,30 a. m. from April 24,2006, the afternoon trading session started at its usual time of 12,30 p. m. Stocks listed on the TSE are separated into the First Section for large companies, the Second Section for mid-sized companies, as of October 31,2010, there are 1,675 First Section companies,437 Second Section companies and 182 Mothers companies. Ninety-four domestic and 10 foreign securities companies participate in TSE trading, see, Members of the Tokyo Stock Exchange Other TSE-related institutions include, The exchanges press club, called the Kabuto Club, which meets on the third floor of the TSE building. Most Kabuto Club members are affiliated with the Nihon Keizai Shimbun, Kyodo News, Jiji Press, or business television broadcasters such as Bloomberg LP, the Kabuto Club is generally busiest during April and May, when public companies release their annual accounts. On 15 June 2007, the TSE paid $303 million to acquire a 4. 99% stake in Singapore Exchange Ltd. The Tokyo Stock Exchange was established on May 15,1878, as the Tokyo Kabushiki Torihikijo under the direction of then-Finance Minister Okuma Shigenobu, trading began on June 1,1878. In 1943, the exchange was combined with ten other stock exchanges in major Japanese cities to form a single Japanese Stock Exchange, the combined exchange was shut down and reorganized shortly after the bombing of Nagasaki. The Tokyo Stock Exchange reopened under its current Japanese name on May 16,1949, a new facility, called TSE Arrows, opened on May 9,2000. In 2010, the TSE launched its Arrowhead trading facility, in 2001, the TSE restructured itself as a stock company, before this time, it was structured as an incorporated association with its members as shareholders. The interruption in trading was the worst in the history of the exchange, trading was suspended for four-and-a-half hours. Mizuho failed to catch the error, the Tokyo Stock Exchange initially blocked attempts to cancel the order, on 11 December, the TSE acknowledged that its system was at fault in the Mizuho trade. On 21 December, Takuo Tsurushima, chief executive of the TSE, and two other senior executives resigned over the Mizuho affair. On January 17,2006, the Nikkei 225 fell 2. 8%, its fastest drop in nine months, the Tokyo Stock Exchange closed early on January 18 due to the trade volume threatening to exceed the exchanges computer systems capacity of 4.5 million trades per day
4.
Frankfurt Stock Exchange
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The Frankfurt Stock Exchange is the worlds 10th largest stock exchange by market capitalization. Located in Frankfurt, Germany, the Frankfurt Stock Exchange is owned and operated by Deutsche Börse AG and it is located in the district of Innenstadt and within the central business district known as Bankenviertel. The trading indices are DAX, DAXplus, CDAX, DivDAX, LDAX, MDAX, SDAX, TecDAX, VDAX, through its Deutsche Börse Cash Market business section, Deutsche Börse AG now operates two trading venues at the Frankfurt Stock Exchange. Xetra is the market for exchange trading in German equities. In 2015,90 per cent of all trading in shares at all German exchanges was transacted through the Xetra, with regard to DAX listings, Xetra has 60 per cent market share throughout Europe. Trading times on trading days are from 9.00 a. m. to 5.30 p. m, the prices on Xetra serve as the basis for calculating the DAX, the best-known German share index. Over 200 trading participants from 16 European countries, plus Hong Kong, Börse Frankfurt is the trading venue for mainly private investors with more than one million securities of German and international issuers. So named Specialists on the trading floor attend to the trading of the securities, trading at the Frankfurt Stock Exchange is governed by clear rules, which apply equally for all trading participants. With a view to improving the continuity of prices and to avoid mistrades, several mechanisms are in place for the trading venues Xetra. These include volatility interruption, market order interruption, and liquidity interruption measures, the origins of the Frankfurt Stock Exchange go back to medieval trade fairs in the 11th century. By the 16th century Frankfurt developed into a wealthy and busy city with a based on trade. In 1585 a bourse was established to set up fixed currency exchange rates, during the following centuries Frankfurt developed into one of the worlds first stock exchanges - next to London and Paris. Bankers like Mayer Amschel Rothschild and Max Warburg had substantial influence on Frankfurts financial trade, in 1879 Frankfurt Stock Exchange moved into its new building at Börsenplatz. During the 1990s the Frankfurt Stock Exchange was also bourse for the Neuer Markt as part of the worldwide dot-com boom, in 1993 the Frankfurter Wertpapierbörse became Deutsche Börse AG, operating businesses for the exchange. Since then the profits from the presence of the European Central Bank in Frankfurt. In 2002 and 2004 Deutsche Börse was in advanced negotiations to take over London Stock Exchange, financial Market Integration in a Wider European Union International financial centres, rivals or partner
5.
Health care
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It includes the work done in providing primary care, secondary care, and tertiary care, as well as in public health. Access to healthcare varies across countries, groups, and individuals, largely influenced by social, countries and jurisdictions have different policies and plans in relation to the personal and population-based health care goals within their societies. Healthcare systems are organizations established to meet the needs of target populations. Their exact configuration varies between national and subnational entities, in some countries and jurisdictions, healthcare planning is distributed among market participants, whereas in others, planning occurs more centrally among governments or other coordinating bodies. Healthcare can contribute to a significant part of a countrys economy. In 2011, the healthcare industry consumed an average of 9.3 percent of the GDP or US$3,322 per capita across the 34 members of OECD countries.1 years, a gain of 10 years since 1970. The USA ranges only on place 26 among the 34 OECD member countries, all OECD countries have achieved universal health coverage, except Mexico and the USA. Healthcare is conventionally regarded as an important determinant in promoting the general physical and mental health, an example of this was the worldwide eradication of smallpox in 1980, declared by the WHO as the first disease in human history to be completely eliminated by deliberate health care interventions. The delivery of health care depends on groups of trained professionals and paraprofessionals coming together as interdisciplinary teams. Healthcare can be defined as public or private. Primary care refers to the work of professionals who act as a first point of consultation for all patients within the health care system. Depending on the nature of the condition, patients may then be referred for secondary or tertiary care. Primary care is used as the term for the health care services which play a role in the local community. It can be provided in different settings, such as Urgent care centres which provide services to patients same day with appointment or walk-in bases, consequently, a primary care practitioner must possess a wide breadth of knowledge in many areas. The International Classification of Primary Care is a tool for understanding and analyzing information on interventions in primary care by the reason for the patient visit. Common chronic illnesses usually treated in primary care may include, for example, hypertension, diabetes, asthma, COPD, depression and anxiety, back pain, Primary care also includes many basic maternal and child health care services, such as family planning services and vaccinations. Physicians in this model bill patients directly for services, either on a monthly, quarterly, or annual basis. Examples of direct primary care practices include Foundation Health in Colorado, the World Health Organization attributes the provision of essential primary care as an integral component of an inclusive primary health care strategy
6.
Osaka
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Osaka is a designated city in the Kansai region of Japan. Historically a merchant city, Osaka has also known as the nations kitchen. Some of the earliest signs of habitation in the Osaka area at the Morinomiya ruins comprise shell mounds, sea oysters. It is believed that what is today the Uehonmachi area consisted of a land with an inland sea in the east. During the Yayoi period, permanent habitation on the plains grew as rice farming became popular, by the Kofun period, Osaka developed into a hub port connecting the region to the western part of Japan. The large numbers of increasingly larger tomb mounds found in the plains of Osaka are seen as evidence of political-power concentration, in 645, Emperor Kōtoku built his Naniwa Nagara-Toyosaki Palace in what is now Osaka, making it the capital of Japan. The city now known as Osaka was at this time referred to as Naniwa, although the capital was moved to Asuka in 655, Naniwa remained a vital connection, by land and sea, between Yamato, Korea, and China. Naniwa was declared the capital again in 744 by order of Emperor Shōmu, and remained so until 745, in 1496, Jōdo Shinshū Buddhists established their headquarters in the heavily fortified Ishiyama Hongan-ji, located directly on the site of the old Naniwa Imperial Palace. Oda Nobunaga began a siege campaign on the temple in 1570 which ultimately resulted in the surrender of the monks. Toyotomi Hideyoshi constructed Osaka Castle in its place in 1583, Osaka was long considered Japans primary economic center, with a large percentage of the population belonging to the merchant class. Over the course of the Edo period, Osaka grew into one of Japans major cities and returned to its ancient role as a lively and its popular culture was closely related to ukiyo-e depictions of life in Edo. By 1780 Osaka had cultivated a vibrant arts culture, as typified by its famous Kabuki, in 1837 Ōshio Heihachirō, a low-ranking samurai, led a peasant insurrection in response to the citys unwillingness to support the many poor and suffering families in the area. Approximately one-quarter of the city was razed before shogunal officials put down the rebellion, Osaka was opened to foreign trade by the government of the Bakufu at the same time as Hyōgo on 1 January 1868, just before the advent of the Boshin War and the Meiji Restoration. Osaka residents were stereotyped in Edo literature from at least the 18th century, jippenisha Ikku in 1802 depicted Osakans as stingy almost beyond belief. Edo writers aspired to samurai culture, and saw themselves as poor but generous, chaste, Edo writers by contrast saw zeeroku as obsequious apprentices, stingy, greedy, gluttonous, and lewd. The modern municipality was established in 1889 by government ordinance, with an area of 15 square kilometres, overlapping todays Chūō. Later, the city went through three major expansions to reach its current size of 223 square kilometres, Osaka was the industrial center most clearly defined in the development of capitalism in Japan. It became known as the Manchester of the Orient, the rapid industrialization attracted many Korean immigrants, who set up a life apart for themselves
7.
United States dollar
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The United States dollar is the official currency of the United States and its insular territories per the United States Constitution. It is divided into 100 smaller cent units, the circulating paper money consists of Federal Reserve Notes that are denominated in United States dollars. The U. S. dollar was originally commodity money of silver as enacted by the Coinage Act of 1792 which determined the dollar to be 371 4/16 grain pure or 416 grain standard silver, the currency most used in international transactions, it is the worlds primary reserve currency. Several countries use it as their currency, and in many others it is the de facto currency. Besides the United States, it is used as the sole currency in two British Overseas Territories in the Caribbean, the British Virgin Islands and Turks and Caicos Islands. A few countries use the Federal Reserve Notes for paper money, while the country mints its own coins, or also accepts U. S. coins that can be used as payment in U. S. dollars. After Nixon shock of 1971, USD became fiat currency, Article I, Section 8 of the U. S. Constitution provides that the Congress has the power To coin money, laws implementing this power are currently codified at 31 U. S. C. Section 5112 prescribes the forms in which the United States dollars should be issued and these coins are both designated in Section 5112 as legal tender in payment of debts. The Sacagawea dollar is one example of the copper alloy dollar, the pure silver dollar is known as the American Silver Eagle. Section 5112 also provides for the minting and issuance of other coins and these other coins are more fully described in Coins of the United States dollar. The Constitution provides that a regular Statement and Account of the Receipts and that provision of the Constitution is made specific by Section 331 of Title 31 of the United States Code. The sums of money reported in the Statements are currently being expressed in U. S. dollars, the U. S. dollar may therefore be described as the unit of account of the United States. The word dollar is one of the words in the first paragraph of Section 9 of Article I of the Constitution, there, dollars is a reference to the Spanish milled dollar, a coin that had a monetary value of 8 Spanish units of currency, or reales. In 1792 the U. S. Congress passed a Coinage Act, Section 20 of the act provided, That the money of account of the United States shall be expressed in dollars, or units. And that all accounts in the offices and all proceedings in the courts of the United States shall be kept and had in conformity to this regulation. In other words, this act designated the United States dollar as the unit of currency of the United States, unlike the Spanish milled dollar the U. S. dollar is based upon a decimal system of values. Both one-dollar coins and notes are produced today, although the form is significantly more common
8.
Japanese yen
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The yen is the official currency of Japan. It is the third most traded currency in the exchange market after the United States dollar. It is also used as a reserve currency after the U. S. dollar, the euro. Before the Meiji Restoration, Japans feudal fiefs all issued their own money, hansatsu, in an array of incompatible denominations. The New Currency Act of 1871 did away with these and established the yen, the former han became prefectures and their mints private chartered banks, which initially retained the right to print money. To bring an end to this situation the Bank of Japan was founded in 1882, following World War II the yen lost much of its prewar value. To stabilize the Japanese economy the exchange rate of the yen was fixed at ¥360 per $1 as part of the Bretton Woods system, when that system was abandoned in 1971, the yen became undervalued and was allowed to float. The yen had appreciated to a peak of ¥271 per $1 in 1973, then underwent periods of depreciation and appreciation due to the 1973 oil crisis, arriving at a value of ¥227 per $1 by 1980. Since 1973, the Japanese government has maintained a policy of intervention. The Japanese government focuses on an export market, and tries to ensure a low yen value through a trade surplus. Since that time, however, the yen has greatly decreased in value, the Bank of Japan maintains a policy of zero to near-zero interest rates and the Japanese government has an extreme anti-inflation policy. Yen derives from the Japanese word 圓, which is cognate with the Chinese yuan, originally, the Chinese had traded silver in mass called sycees and when Spanish and Mexican silver coins arrived, the Chinese called them silver rounds for their circular shapes. The coins and the name appeared in Japan. While the Chinese eventually replaced 圓 with 元, the Japanese continued to use the same word, the spelling and pronunciation yen is standard in English. This is because mainly English speakers who visited Japan at the end of the Edo period to the early Meiji period spelled words this way, ゑん /wen/ in historical kana orthography. In the 16th century, Japanese /e/ and /we/ both had been pronounced and Portuguese missionaries had spelled them ye, some time thereafter, by the middle of the 18th century, /e/ and /we/ came to be pronounced as in modern Japanese, although some regions retain the pronunciation. In the early Meiji era, James Curtis Hepburn, following Medhurst, spelled all es as ye in his A Japanese and that was the first full-scale Japanese-English/English-Japanese dictionary, which had a strong influence on Westerners in Japan and probably prompted the spelling yen. Hepburn revised most of yes to e in the 3rd edition in order to mirror the contemporary pronunciation and this was probably already fixed and has remained so ever since
9.
Medical thermometer
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A medical thermometer is used for measuring human or animal body temperature. The tip of the thermometer is inserted into the mouth under the tongue, under the armpit, the medical thermometer began as an instrument more appropriately called a water thermoscope, constructed by Galileo Galilei circa 1592–1593. It lacked an accurate scale with which to measure temperature and could be affected by changes in atmospheric pressure. Italian physician Santorio Santorio is the first known individual to have put a scale on the thermoscope and wrote of it in 1625. His models were bulky, impractical and took an amount of time to take an accurate oral reading of the patients temperature. There are two men who switched out water for alcohol in the thermometer. The earliest is Ferdinando II de Medici, Grand Duke of Tuscany, daniel Gabriel Fahrenheit, a Polish-born German physicist, engineer, and glass blower, made contributions to thermometers as well. He created an alcohol thermometer in 1709 and later innovated the mercury thermometer in 1714, mercury, he found, responded more quickly to temperature changes than the previously used water. Fahrenheit also created the scale which is named after him. The scale is only mainly used for everyday applications in the United States, its territories and associated states as well as the Bahamas, Belize. By 1742 Swedish astronomer Anders Celsius created the Celsius temperature scale that was the reverse of the scale, in that 0 was the boiling point of water. It would later be reversed by Swedish botanist Carolus Linnaeus in 1744, on 19 May 1743 he published the design of a mercury thermometer, the Thermometer of Lyon built by the craftsman Pierre Casati that used this scale. The medical thermometer was used by Dutch chemist and physician Hermann Boerhaave, as well as his notable students Gerard van Swieten and it was also utilized around the same time by Scottish physician George Martine. De Haen made particular strides in medicine with the thermometer, by observing the correlation in a patients change in temperature and the physical symptoms of the illness, he concluded that a record of ones temperature could inform the doctor of a patients health. However, his proposals were not met with enthusiasm by his peers, thermometers remained cumbersome to transport and use. By the mid 19th century, the medical thermometer was still a foot long, with his findings, he was able to conclude a healthy humans temperature fell within the range of 36.3 to 37.5 °C. Dr. Theodor H. Benzinger invented the ear thermometer in 1964, born in Stuttgart, Germany, he immigrated to the U. S. in 1947 and became a naturalized citizen in 1955. He worked from 1947 to 1970 in the division at the Naval Medical Research Center in Bethesda
10.
Sphygmomanometer
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It is always used in conjunction with a means to determine at what pressure blood flow is just starting, and at what pressure it is unimpeded. Manual sphygmomanometers are used in conjunction with a stethoscope, a sphygmomanometer consists of an inflatable cuff, a measuring unit, and a mechanism for inflation which may be a manually operated bulb and valve or a pump operated electrically. There are three types of sphygmomanometers, Manual sphygmomanometers require a stethoscope for auscultation and they are used by trained practitioners. It is possible to obtain a basic reading through palpation alone, mercury sphygmomanometers are considered the gold standard. They show blood pressure by affecting the height of a column of mercury, because of their accuracy, they are often used in clinical trials of drugs and in clinical evaluations of high-risk patients, including pregnant women. Aneroid sphygmomanometers are in use, they may require calibration checks. Aneroid sphygmomanometers are considered safer than mercury sphygmomanometers, although inexpensive ones are less accurate, a major cause of departure from calibration is mechanical jarring. Aneroids mounted on walls or stands are not susceptible to this particular problem, digital, using oscillometric measurements and electronic calculations rather than auscultation. They may use manual or automatic inflation and these are electronic, are easy to operate without training, and can be used in noisy environments, they are not as accurate as mercury instruments. They measure systolic and diastolic pressures by oscillometric detection, using a pressure sensor and electronic components. They do not measure systolic and diastolic pressures directly, but calculate them from the mean pressure, calibration is also a concern for these instruments. Most instruments also display pulse rate, people measuring blood pressure in patients with these conditions should use analog sphygmomanometers, because, when used by a trained person, they are more accurate than digital sphygmomanometers. Digital instruments may use a cuff placed, in order of accuracy and inverse order of portability and convenience, around the upper arm, some instruments are claimed also to measure arterial stiffness. Some of these monitors also detect irregular heartbeats, in humans, the cuff is normally placed smoothly and snugly around an upper arm, at roughly the same vertical height as the heart while the subject is seated with the arm supported. Other sites of placement depend on species, it may include the flipper or tail and it is essential that the correct size of cuff is selected for the patient. Too small a cuff results in too high a pressure, while too large a cuff results in too low a pressure. For clinical measurements it is usual to measure and record both arms in the consultation to determine if the pressure is significantly higher in one arm than the other. A difference of 10 mm Hg may be a sign of coarctation of the aorta, if the arms read differently, the higher reading arm would be used for later readings
11.
Nebulizer
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In medicine, a nebuliser or nebulizer is a drug delivery device used to administer medication in the form of a mist inhaled into the lungs. Nebulizers are commonly used for the treatment of cystic fibrosis, asthma, COPD, analytical nebulizers are another form of nebulizer and are used primarily in laboratory settings for elemental analysis. Nebulizers use oxygen, compressed air or ultrasonic power to break up solutions and suspensions into small droplets that can be directly inhaled from the mouthpiece of the device. The definition of an aerosol is a mixture of gas and liquid particles, the European Respiratory Society acknowledge that although nebulizers are used in hospitals and at home they suggest much of this use may not be evidence-based. Recent evidence show that nebulizers are no more effective than metered-dose inhalers with spacers and those findings refer specifically to the treatment of asthma and not to the efficacy of nebulisers generally, as for COPD for example. For COPD, especially when assessing exacerbations or lung attacks, evidence shows no benefit from MDIs over nebulizers, European Respiratory Society highlighted a risk relating to droplet size reproducibility caused by selling nebulizer devices separately from nebulized solution. They found this practice could vary droplet size 10-fold or more by changing from an inefficient nebulizer system to an efficient one. In addition, another found that a MDI had a lower required dose for clinical result compared to a nebulizer. The lung deposition characteristics and efficacy of an aerosol depend largely on the particle or droplet size, generally, the smaller the particle the greater its chance of peripheral penetration and retention. However, for fine particles below 0.5 µm in diameter there is a chance of avoiding deposition altogether. In 1966 the Task Group on Lung Dynamics, concerned mainly with the hazards of inhalation of environmental toxins, the medical company also invented a new device named Respimat Soft Mist Inhaler in 1997. The device features no gas propellant and no need for battery/power to operate, the average droplet size in the mist was measured to a somewhat disappointing 5.8 micrometers, which could indicate some potential efficiency problems for the inhaled medicine to reach the lungs. Subsequent trials have proven this was not the case, due to the very low velocity of the mist, the Soft Mist Inhaler in fact has a higher efficiency compared to a conventional pMDI. Commercial nebulizers typically use a compressor to maintain their rate of airflow. The most commonly used nebulizers are jet nebulizers, which are also called atomizers, however jet nebulizers are commonly used for patients in hospitals who have difficulty using inhalers, such as in serious cases of respiratory disease, or severe asthma attacks. The main advantage of the jet nebulizer is related to its low operational cost, if the patient needs to inhale medicine on a daily basis the use of a pMDI can be rather expensive. Today several manufacturers have managed to lower the weight of the jet nebulizer down to 635 grams. Compared to all the competing inhalers and nebulizers, the noise, trade names for jet nebulizers include Maxin
12.
Turnstile
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A turnstile, also called a baffle gate or turnstyle, is a form of gate which allows one person to pass at a time. It can also be made so as to enforce one-way traffic of people, and in addition, it can restrict passage only to people who insert a coin, a ticket, a pass, or similar. Turnstiles were originally used, like other forms of stile, to human beings to pass while keeping sheep or other livestock penned in. The use of turnstiles in most modern applications has been credited to Clarence Saunders, turnstiles are used at a wide variety of settings, including stadiums, amusement parks, mass transit stations, office lobbies, airports, ski resorts, and casinos. From a business/revenue standpoint, turnstiles give an accurate, verifiable count of attendance, from a security standpoint, they lead patrons to enter single-file, so security personnel have a clear view of each patron. This enables security to efficiently isolate potential trouble or to confiscate any prohibited materials, on the other hand, physical barriers become a serious safety issue when a speedy evacuation is needed, requiring emergency exits that bypass any turnstiles. Persons with disabilities may have difficulties using turnstiles, in these cases, generally a wide aisle gate or a manual gate may be provided. At some locations where luggage is expected, a line of turnstiles may be formed of wide aisle gates. Turnstiles often use ratchet mechanisms to allow the rotation of the stile in one direction allowing ingress, turnstiles are often used for counting the numbers of people passing through a gate, even when payment is not involved. They are used extensively in this manner in amusement parks, in order to track of how many people enter and exit the park. The first major use of turnstiles at a venue was at Hampden Park in Glasgow. A turnstile used in fairs, attractions, and arenas, sometimes also referred to as half-height turnstiles, this fixed arm style has traditionally been the most popular type of turnstile. There are many variations of this available, including one which is designed to be accompanied by a matching ticket box. Some styles are designed to allow entry only after a payment are inserted, a disadvantage to this type is people can jump the turnstile, as happens commonly on the Moscow Metro and other mass transport systems in Russia. Optical turnstiles are an alternative to the traditional arm-style turnstile and are used in locations where a physical barrier is deemed unnecessary or unaesthetic. Optical turnstiles generally use a beam to count patrons and recognize anyone attempting to enter a site without a valid entry pass. The drop arm optical turnstile is a combination of the security of a tripod or barrier turnstile, the lanes can have either single or double arms. When access is granted the arms drop into recesses in the cabinet, once the arms drop out of the way, the turnstile functions as a fully optical turnstile
$ 8.279 billion USD (FY 2015)
(¥ 833.60 billion JPY) (FY 2015)
