An orbital spaceflight is a spaceflight in which a spacecraft is placed on a trajectory where it could remain in space for at least one orbit. To do this around the Earth, it must be on a free trajectory which has an altitude at perigee around 80 kilometers (50 mi); this is the boundary of space as defined by NASA, the US Air Force and the FAA. To remain in orbit at this altitude requires an orbital speed of ~7.8 km/s. Orbital speed is slower for higher orbits, but attaining them requires greater delta-v. The Fédération Aéronautique Internationale has established the Kármán line at an altitude of 100 km (62 mi) as a working definition for the boundary between aeronautics and astronautics. This is used because at an altitude of about 100 km (62 mi), as Theodore von Kármán calculated, a vehicle would have to travel faster than orbital velocity to derive sufficient aerodynamic lift from the atmosphere to support itself.

Spaceflight is an application of astronautics to fly objects, usually spacecraft, into or through outer space, either with or without humans on board. Most spaceflight is uncrewed and conducted mainly with spacecraft such as satellites in orbit around Earth, but also includes space probes for flights beyond Earth orbit. Such spaceflight operate either by telerobotic or autonomous control. The more complex human spaceflight has been pursued soon after the first orbital satellites and has reached the Moon and permanent human presence in space around Earth, particularly with the use of space stations. Human spaceflight programs include the Soyuz, Shenzhou, the past Apollo Moon landing and the Space Shuttle programs. Other current spaceflight are conducted to the International Space Station and to China's Tiangong Space Station.