Otis Ray Bowen was an American politician and physician who served as the 44th Governor of Indiana from 1973 to 1981 and as Secretary of Health and Human Services in the Cabinet of President Ronald Reagan from 1985 to 1989.

The United States secretary of health and human services is the head of the United States Department of Health and Human Services, and serves as the principal advisor to the president of the United States on all health matters. The secretary is a member of the United States Cabinet. The office was formerly Secretary of Health, Education, and Welfare. In 1980, the Department of Health, Education, and Welfare was renamed the Department of Health and Human Services, and its education functions and Rehabilitation Services Administration were transferred to the new United States Department of Education. Patricia Roberts Harris headed the department before and after it was renamed.