Our Lady Immaculate and St Joseph Church is a Roman Catholic parish church in Prescot, Merseyside. It was built in 1856-57 by the Society of Jesus, and is now in the Knowsley deanery of the Archdiocese of Liverpool. It is a Grade II listed building, designed by Joseph Aloysius Hansom, and is next to the Church of St Mary on Vicarage Place in the centre of Prescot.

Prescot is a town and civil parish within the Metropolitan Borough of Knowsley in Merseyside, United Kingdom. It lies about eight miles (13 km) to the east of Liverpool city centre. At the 2001 Census, the civil parish population was 11,184. The population of the larger Prescot East and West wards at the 2011 census totalled 14,139. Prescot marks the beginning of the A58 road which runs through to Wetherby, near Leeds in West Yorkshire. The town is served by Prescot railway station and Eccleston Park railway station in neighbouring Eccleston.