The POWER4 is a microprocessor developed by International Business Machines (IBM) that implemented the 64-bit PowerPC and PowerPC AS instruction set architectures. Released in 2001, the POWER4 succeeded the POWER3 and RS64 microprocessors, enabling RS/6000 and eServer iSeries models of AS/400 computer servers to run on the same processor, as a step toward converging the two lines. The POWER4 was a multicore microprocessor, with two cores on a single die, the first non-embedded microprocessor to do so. POWER4 Chip was first commercially available multiprocessor chip. The original POWER4 had a clock speed of 1.1 and 1.3 GHz, while an enhanced version, the POWER4+, reached a clock speed of 1.9 GHz. The PowerPC 970 is a derivative of the POWER4.

PowerPC is a reduced instruction set computer (RISC) instruction set architecture (ISA) created by the 1991 Apple–IBM–Motorola alliance, known as AIM. PowerPC, as an evolving instruction set, has been named Power ISA since 2006, while the old name lives on as a trademark for some implementations of Power Architecture–based processors.