Pan-Indianism is a philosophical and political approach promoting unity, and to some extent cultural homogenization, among different Indigenous groups in the Americas regardless of tribal distinctions and cultural differences.

Tecumseh's confederacy was a confederation of indigenous peoples in the Great Lakes region of North America that began to form in the early 19th century around the teaching of Tenskwatawa, called The Prophet by his followers. The confederation grew over several years and came to include several thousand warriors. Shawnee leader Tecumseh, the brother of The Prophet, developed into the leader of the group as early as 1808. Together, they worked to unite the various tribes against the European settlers who had been crossing the Appalachian Mountains and settling on their land.