Pennsylvania Route 144 is a state highway located in the U.S. state of Pennsylvania, covering a distance of about 109 miles (175 km). The southern terminus is located near an interchange with U.S. Route 322 (US 322) at State Route 2015 in Potter Township while the northern terminus is located at US 6 in Galeton. Between Snow Shoe and Renovo, PA 144 is known as the High Plateau Scenic Byway, a Pennsylvania Scenic Byway.

Pennsylvania Route 45 is an 86-mile-long (138 km) state highway that is located in central Pennsylvania, United States. The western terminus of the route is situated at PA 453 in Morris Township near the community of Water Street. The eastern terminus is located at PA 642 west of the small town of Mooresburg.