The Pere Marquette was a streamlined passenger train operated by the Pere Marquette Railway and its successor the Chesapeake and Ohio Railway (C&O) between Detroit and Grand Rapids, Michigan. It operated from 1946 to 1971. It was the first new streamliner to enter service after World War II. Although discontinued in 1971 on the formation of Amtrak, in 1984 Amtrak revived the name for a new train between Chicago, Illinois and Grand Rapids.

The Pere Marquette Railway was a railroad that operated in the Great Lakes region of the United States and southern parts of Ontario in Canada. It had trackage in the states of Michigan, Ohio, Indiana, and the Canadian province of Ontario. Its primary connections included Buffalo; Toledo; and Chicago. The company was named after Jacques Marquette, a French Jesuit missionary who founded Michigan's first European settlement, Sault Ste Marie.