The Philippine General Hospital, simply referred to as UP–PGH or PGH, is a tertiary state-owned hospital administered and operated by the University of the Philippines Manila. It is designated as the National University Hospital, and the national government referral center. It stands within a 10-hectare (25-acre) site located at the UP Manila Campus in Ermita, Manila. PGH has 1,100 beds and 400 private beds, and has an estimated of 4,000 employees to serve more than 600,000 patients every year.

The University of the Philippines is a state university system in the Philippines. It is the country's national university, as mandated by Republic Act No. 9500, giving it institutional autonomy.