Phosphatidylinositol
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Phosphatidylinositol or inositol phospholipid is a biomolecule. It was initially called "inosite" when it was discovered by Léon Maquenne and Johann Joseph von Scherer in the late 19th century. It was
Phosphatidylinositol structure with components
The process of hydrolysis and biosynthesis of PI separated between the plasma membrane and endoplasmic reticulum (ER), depicting respective enzymatic processes and reactions.
Lipid signaling
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Lipid signaling, broadly defined, refers to any biological cell signaling event involving a lipid messenger that binds a protein target, such as a receptor, kinase or phosphatase, which in turn mediat
Phosphatidylinositol
…substituted with an inositol polar head group. Phosphorylated forms of phosphatidylinositol (PI) are called phosphoinositides and play important roles in lipid signaling, cell signaling and membrane trafficking. The inositol ring can be phosphorylated by a variety of kinases on the three, four and five hydroxyl groups…
Cartoon of second messenger systems. Figure adapted From Barbraham Institute Mike Berridge. https://web.archive.org/web/20090323190124/http://www.babraham.ac.uk/emeritus/berridge.html (accessed Jan. 21, 2008).