1.
Melting point
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The melting point of a solid is the temperature at which it changes state from solid to liquid at atmospheric pressure. At the melting point the solid and liquid phase exist in equilibrium, the melting point of a substance depends on pressure and is usually specified at standard pressure. When considered as the temperature of the change from liquid to solid. Because of the ability of some substances to supercool, the point is not considered as a characteristic property of a substance. For most substances, melting and freezing points are approximately equal, for example, the melting point and freezing point of mercury is 234.32 kelvins. However, certain substances possess differing solid-liquid transition temperatures, for example, agar melts at 85 °C and solidifies from 31 °C to 40 °C, such direction dependence is known as hysteresis. The melting point of ice at 1 atmosphere of pressure is close to 0 °C. In the presence of nucleating substances the freezing point of water is the same as the melting point, the chemical element with the highest melting point is tungsten, at 3687 K, this property makes tungsten excellent for use as filaments in light bulbs. Many laboratory techniques exist for the determination of melting points, a Kofler bench is a metal strip with a temperature gradient. Any substance can be placed on a section of the strip revealing its thermal behaviour at the temperature at that point, differential scanning calorimetry gives information on melting point together with its enthalpy of fusion. A basic melting point apparatus for the analysis of crystalline solids consists of an oil bath with a transparent window, the several grains of a solid are placed in a thin glass tube and partially immersed in the oil bath. The oil bath is heated and with the aid of the melting of the individual crystals at a certain temperature can be observed. In large/small devices, the sample is placed in a heating block, the measurement can also be made continuously with an operating process. For instance, oil refineries measure the point of diesel fuel online, meaning that the sample is taken from the process. This allows for more frequent measurements as the sample does not have to be manually collected, for refractory materials the extremely high melting point may be determined by heating the material in a black body furnace and measuring the black-body temperature with an optical pyrometer. For the highest melting materials, this may require extrapolation by several hundred degrees, the spectral radiance from an incandescent body is known to be a function of its temperature. An optical pyrometer matches the radiance of a body under study to the radiance of a source that has been previously calibrated as a function of temperature, in this way, the measurement of the absolute magnitude of the intensity of radiation is unnecessary. However, known temperatures must be used to determine the calibration of the pyrometer, for temperatures above the calibration range of the source, an extrapolation technique must be employed
2.
France
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France, officially the French Republic, is a country with territory in western Europe and several overseas regions and territories. The European, or metropolitan, area of France extends from the Mediterranean Sea to the English Channel and the North Sea, Overseas France include French Guiana on the South American continent and several island territories in the Atlantic, Pacific and Indian oceans. France spans 643,801 square kilometres and had a population of almost 67 million people as of January 2017. It is a unitary republic with the capital in Paris. Other major urban centres include Marseille, Lyon, Lille, Nice, Toulouse, during the Iron Age, what is now metropolitan France was inhabited by the Gauls, a Celtic people. The area was annexed in 51 BC by Rome, which held Gaul until 486, France emerged as a major European power in the Late Middle Ages, with its victory in the Hundred Years War strengthening state-building and political centralisation. During the Renaissance, French culture flourished and a colonial empire was established. The 16th century was dominated by civil wars between Catholics and Protestants. France became Europes dominant cultural, political, and military power under Louis XIV, in the 19th century Napoleon took power and established the First French Empire, whose subsequent Napoleonic Wars shaped the course of continental Europe. Following the collapse of the Empire, France endured a succession of governments culminating with the establishment of the French Third Republic in 1870. Following liberation in 1944, a Fourth Republic was established and later dissolved in the course of the Algerian War, the Fifth Republic, led by Charles de Gaulle, was formed in 1958 and remains to this day. Algeria and nearly all the colonies became independent in the 1960s with minimal controversy and typically retained close economic. France has long been a centre of art, science. It hosts Europes fourth-largest number of cultural UNESCO World Heritage Sites and receives around 83 million foreign tourists annually, France is a developed country with the worlds sixth-largest economy by nominal GDP and ninth-largest by purchasing power parity. In terms of household wealth, it ranks fourth in the world. France performs well in international rankings of education, health care, life expectancy, France remains a great power in the world, being one of the five permanent members of the United Nations Security Council with the power to veto and an official nuclear-weapon state. It is a member state of the European Union and the Eurozone. It is also a member of the Group of 7, North Atlantic Treaty Organization, Organisation for Economic Co-operation and Development, the World Trade Organization, originally applied to the whole Frankish Empire, the name France comes from the Latin Francia, or country of the Franks
3.
Chemist
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A chemist is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties, chemists carefully describe the properties they study in terms of quantities, with detail on the level of molecules and their component atoms. Chemists carefully measure substance proportions, reaction rates, and other chemical properties, the word chemist is also used to address Pharmacists in Commonwealth English. Chemists may specialize in any number of subdisciplines of chemistry, materials scientists and metallurgists share much of the same education and skills with chemists. The roots of chemistry can be traced to the phenomenon of burning, fire was a mystical force that transformed one substance into another and thus was of primary interest to mankind. It was fire that led to the discovery of iron and glasses, after gold was discovered and became a precious metal, many people were interested to find a method that could convert other substances into gold. This led to the protoscience called alchemy, the word chemist is derived from the New Latin noun chimista, an abbreviation of alchimista. Alchemists discovered many chemical processes that led to the development of modern chemistry, Chemistry as we know it today, was invented by Antoine Lavoisier with his law of conservation of mass in 1783. The discoveries of the elements has a long history culminating in the creation of the periodic table by Dmitri Mendeleev. The Nobel Prize in Chemistry created in 1901 gives an excellent overview of chemical discovery since the start of the 20th century. Jobs for chemists usually require at least a degree, but many positions, especially those in research. At the Masters level and higher, students tend to specialize in a particular field, postdoctoral experience may be required for certain positions. Workers whose work involves chemistry, but not at a complexity requiring an education with a degree, are commonly referred to as chemical technicians. Such technicians commonly do such work as simpler, routine analyses for quality control or in clinical laboratories, there are also degrees specific to become a Chemical Technologist, which are somewhat distinct from those required when a student is interested in becoming a professional Chemist. A Chemical technologist is more involved in the management and operation of the equipment and they are part of the team of a chemical laboratory in which the quality of the raw material, intermediate products and finished products is analyzed. They also perform functions in the areas of quality control. The higher the level achieved in the field of Chemistry, the higher the responsibility given to that chemist. Chemistry, as a field, have so many applications that different tasks/objectives can be given to workers/scientists with these different levels of education and/or experience
4.
Redox
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Redox is a chemical reaction in which the oxidation states of atoms are changed. Any such reaction involves both a process and a complementary oxidation process, two key concepts involved with electron transfer processes. Redox reactions include all chemical reactions in which atoms have their oxidation state changed, in general, the chemical species from which the electron is stripped is said to have been oxidized, while the chemical species to which the electron is added is said to have been reduced. It can be explained in terms, Oxidation is the loss of electrons or an increase in oxidation state by a molecule, atom. Reduction is the gain of electrons or a decrease in state by a molecule, atom. As an example, during the combustion of wood, oxygen from the air is reduced, the reaction can occur relatively slowly, as in the case of rust, or more quickly, as in the case of fire. Redox is a portmanteau of reduction and oxidation, the word oxidation originally implied reaction with oxygen to form an oxide, since dioxygen was historically the first recognized oxidizing agent. Later, the term was expanded to encompass oxygen-like substances that accomplished parallel chemical reactions, ultimately, the meaning was generalized to include all processes involving loss of electrons. The word reduction originally referred to the loss in weight upon heating a metallic ore such as an oxide to extract the metal. In other words, ore was reduced to metal, antoine Lavoisier showed that this loss of weight was due to the loss of oxygen as a gas. Later, scientists realized that the atom gains electrons in this process. The meaning of reduction then became generalized to all processes involving gain of electrons. Even though reduction seems counter-intuitive when speaking of the gain of electrons, it help to think of reduction as the loss of oxygen. Since electrons are charged, it is also helpful to think of this as reduction in electrical charge. The electrochemist John Bockris has used the words electronation and deelectronation to describe reduction and oxidation processes respectively when they occur at electrodes and these words are analogous to protonation and deprotonation, but they have not been widely adopted by chemists. The term hydrogenation could be used instead of reduction, since hydrogen is the agent in a large number of reactions. But, unlike oxidation, which has been generalized beyond its root element, the word redox was first used in 1928. The processes of oxidation and reduction occur simultaneously and cannot happen independently of one another, the oxidation alone and the reduction alone are each called a half-reaction, because two half-reactions always occur together to form a whole reaction
5.
Switzerland
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Switzerland, officially the Swiss Confederation, is a federal republic in Europe. It consists of 26 cantons, and the city of Bern is the seat of the federal authorities. The country is situated in western-Central Europe, and is bordered by Italy to the south, France to the west, Germany to the north, and Austria and Liechtenstein to the east. Switzerland is a country geographically divided between the Alps, the Swiss Plateau and the Jura, spanning an area of 41,285 km2. The establishment of the Old Swiss Confederacy dates to the medieval period, resulting from a series of military successes against Austria. Swiss independence from the Holy Roman Empire was formally recognized in the Peace of Westphalia in 1648. The country has a history of armed neutrality going back to the Reformation, it has not been in a state of war internationally since 1815, nevertheless, it pursues an active foreign policy and is frequently involved in peace-building processes around the world. In addition to being the birthplace of the Red Cross, Switzerland is home to international organisations. On the European level, it is a member of the European Free Trade Association. However, it participates in the Schengen Area and the European Single Market through bilateral treaties, spanning the intersection of Germanic and Romance Europe, Switzerland comprises four main linguistic and cultural regions, German, French, Italian and Romansh. Due to its diversity, Switzerland is known by a variety of native names, Schweiz, Suisse, Svizzera. On coins and stamps, Latin is used instead of the four living languages, Switzerland is one of the most developed countries in the world, with the highest nominal wealth per adult and the eighth-highest per capita gross domestic product according to the IMF. Zürich and Geneva have each been ranked among the top cities in the world in terms of quality of life, with the former ranked second globally, according to Mercer. The English name Switzerland is a compound containing Switzer, a term for the Swiss. The English adjective Swiss is a loan from French Suisse, also in use since the 16th century. The name Switzer is from the Alemannic Schwiizer, in origin an inhabitant of Schwyz and its associated territory, the Swiss began to adopt the name for themselves after the Swabian War of 1499, used alongside the term for Confederates, Eidgenossen, used since the 14th century. The data code for Switzerland, CH, is derived from Latin Confoederatio Helvetica. The toponym Schwyz itself was first attested in 972, as Old High German Suittes, ultimately related to swedan ‘to burn’
6.
Analytical chemistry
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Analytical chemistry studies and uses instruments and methods used to separate, identify, and quantify matter. In practice separation, identification or quantification may constitute the entire analysis or be combined with another method, qualitative analysis identifies analytes, while quantitative analysis determines the numerical amount or concentration. Analytical chemistry consists of classical, wet chemical methods and modern, classical qualitative methods use separations such as precipitation, extraction, and distillation. Identification may be based on differences in color, odor, melting point, boiling point, classical quantitative analysis uses mass or volume changes to quantify amount. Instrumental methods may be used to separate samples using chromatography, electrophoresis or field flow fractionation, then qualitative and quantitative analysis can be performed, often with the same instrument and may use light interaction, heat interaction, electric fields or magnetic fields. Often the same instrument can separate, identify and quantify an analyte, Analytical chemistry is also focused on improvements in experimental design, chemometrics, and the creation of new measurement tools. Analytical chemistry has applications to forensics, medicine, science. Analytical chemistry has been important since the days of chemistry, providing methods for determining which elements. The first instrumental analysis was flame emissive spectrometry developed by Robert Bunsen, most of the major developments in analytical chemistry take place after 1900. During this period instrumental analysis becomes progressively dominant in the field, in particular many of the basic spectroscopic and spectrometric techniques were discovered in the early 20th century and refined in the late 20th century. The separation sciences follow a similar line of development and also become increasingly transformed into high performance instruments. In the 1970s many of these began to be used together as hybrid techniques to achieve a complete characterization of samples. Lasers have been used in chemistry as probes and even to initiate. Modern analytical chemistry is dominated by instrumental analysis, many analytical chemists focus on a single type of instrument. Academics tend to focus on new applications and discoveries or on new methods of analysis. The discovery of a present in blood that increases the risk of cancer would be a discovery that an analytical chemist might be involved in. An effort to develop a new method might involve the use of a laser to increase the specificity and sensitivity of a spectrometric method. Many methods, once developed, are kept purposely static so that data can be compared over long periods of time and this is particularly true in industrial quality assurance, forensic and environmental applications
7.
Phthalate
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Phthalates, or phthalate esters, are esters of phthalic acid and are mainly used as plasticizers. Phthalates are manufactured by reacting phthalic anhydride with alcohol that range from methanol and ethanol up to tridecyl alcohol and they are divided into two distinct groups, with very different applications, toxicological properties, and classification, based on the number of carbon atoms in their alcohol chain. They are used primarily to soften polyvinyl chloride, lower-molecular-weight phthalates are being gradually replaced in many products in the United States, Canada, and European Union over health concerns. They are replaced by high-molecular-weight phthalates, Phthalates are used in a wide range of common products, and are released into the environment. There is no covalent bond between the phthalates and plastics, rather, they are entangled within the plastic as a result of the process used to make PVC articles. They can be removed by exposure to heat or with organic solvents, phthalate exposure may be through direct use or by indirect means through leaching and general environmental contamination. Diet is believed to be the source of di phthalate. Fatty foods such as milk, butter, and meats are a major source, in studies of rodents exposed to certain phthalates, high doses have been shown to change hormone levels and cause birth defects. Phthalates are also used in soft plastic fishing lures, caulk, paint pigments. Phthalates are used in a variety of applications such as shower curtains, vinyl upholstery, adhesives, floor tiles, food containers and wrappers. Personal-care items containing phthalates include perfume, eye shadow, moisturizer, nail polish, liquid soap, Phthalates are also found in modern electronics and medical applications such as catheters and blood transfusion devices. The most widely used phthalates are di phthalate, diisodecyl phthalate, DEHP was the dominant plasticizer used globally in PVC due to its low cost. Benzylbutylphthalate is used in the manufacture of foamed PVC, which is used mostly as a flooring material, Phthalates with small R and R groups are used as solvents in perfumes and pesticides. Approximately 8.4 million tonnes of plasticizers are consumed every year. Approximately 70% of those totals are phthalates, down from about 88% in 2005, the remaining 30% are alternative chemistries. Plasticizers contribute 10-60% of total weight of plasticized products, all of these mentioned phthalates are now regulated and restricted in many products. Analysis of such applications will involve studies on alternatives and, given the number of compounds that have been used as plasticizers. The development of cellulose nitrate plastic in 1846 led to the patent of castor oil in 1856 for use as the first plasticizer, in 1870, camphor became the more favored plasticizer for cellulose nitrate
8.
Potassium dichromate
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Potassium dichromate, K2Cr2O7, is a common inorganic chemical reagent, most commonly used as an oxidizing agent in various laboratory and industrial applications. As with all hexavalent chromium compounds, it is acutely and chronically harmful to health and it is a crystalline ionic solid with a very bright, red-orange color. The salt is popular in the laboratory because it is not deliquescent, potassium dichromate is usually prepared by the reaction of potassium chloride on sodium dichromate. Alternatively, it can be obtained from potassium chromate by roasting chrome ore with potassium hydroxide and it is used to oxidize alcohols. It converts primary alcohols into aldehydes and, under more forcing conditions, in contrast, potassium permanganate tends to give carboxylic acids as the sole products. Secondary alcohols are converted into ketones, for example, menthone may be prepared by oxidation of menthol with acidified dichromate. In an aqueous solution the color change exhibited can be used to test for distinguishing aldehydes from ketones, aldehydes reduce dichromate from the +6 to the +3 oxidation state, changing color from orange to green. This color change arises because the aldehyde can be oxidized to the carboxylic acid. A ketone will show no such change because it cannot be oxidized further, when heated strongly, it decomposes with the evolution of oxygen. 4K2Cr2O7 → 4K2CrO4 + 2Cr2O3 + 3O2 When an alkali is added to a red solution containing dichromate ions. For example, potassium chromate is produced industrially using potash, K2Cr2O7 + K2CO3 →2 K2CrO4 + CO2 The reaction is reversible, the main use is as a precursor to potassium chrome alum, used in leather tanning. Like other chromium compounds, potassium dichromate has been used to prepare chromic acid for cleaning glassware, because of safety concerns associated with hexavalent chromium, this practice has been largely discontinued. It is used as an ingredient in cement in which it retards the setting of the mixture and improves its density and this usage commonly causes contact dermatitis in construction workers. Potassium dichromate has uses in photography and in screen printing. In 1852, Henry Fox Talbot discovered that exposure to light in the presence of potassium dichromate hardened organic colloids such as gelatin and gum arabic. These discoveries soon led to the print, gum bichromate. Some processes depended on the only, in combination with the differential absorption of certain dyes by the hardened or unhardened areas. Dichromated colloids were also used as photoresists in various industrial applications and this solution reconverts the elemental silver particles in the film to silver chloride
9.
Jmol
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Jmol is computer software for molecular modelling chemical structures in 3-dimensions. Jmol returns a 3D representation of a molecule that may be used as a teaching tool and it is written in the programming language Java, so it can run on the operating systems Windows, macOS, Linux, and Unix, if Java is installed. It is free and open-source software released under a GNU Lesser General Public License version 2.0, a standalone application and a software development kit exist that can be integrated into other Java applications, such as Bioclipse and Taverna. A popular feature is an applet that can be integrated into web pages to display molecules in a variety of ways, for example, molecules can be displayed as ball-and-stick models, space-filling models, ribbon diagrams, etc. Jmol supports a range of chemical file formats, including Protein Data Bank, Crystallographic Information File, MDL Molfile. There is also a JavaScript-only version, JSmol, that can be used on computers with no Java, the Jmol applet, among other abilities, offers an alternative to the Chime plug-in, which is no longer under active development. While Jmol has many features that Chime lacks, it does not claim to reproduce all Chime functions, most notably, Chime requires plug-in installation and Internet Explorer 6.0 or Firefox 2.0 on Microsoft Windows, or Netscape Communicator 4.8 on Mac OS9. Jmol requires Java installation and operates on a variety of platforms. For example, Jmol is fully functional in Mozilla Firefox, Internet Explorer, Opera, Google Chrome, fast and Scriptable Molecular Graphics in Web Browsers without Java3D
10.
Potassium permanganate
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Potassium permanganate is an inorganic chemical compound and medication. As a medication it is used for cleaning wounds and dermatitis and it has the chemical formula KMnO4 and is a salt consisting of K+ and MnO−4 ions. It is an oxidizing agent. It dissolves in water to give intensely pink or purple solutions, in 2000, worldwide production was estimated at 30,000 tonnes. In this compound, manganese is in the +7 oxidation state and it is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system. The wholesale cost in the world is about 0.01 USD per gram of powder. In the United Kingdom a 400 milligram tablet costs the NHS roughly £0.51, almost all applications of potassium permanganate exploit its oxidizing properties. As a strong oxidant that does not generate toxic byproducts, KMnO4 has many niche uses, as an oxidant, potassium permanganate can act as an antiseptic. For example, dilute solutions are used to treat sores, disinfectant for the hands and treatment for mild pompholyx, dermatitis. Potassium permanganate is used extensively in the treatment industry. It is used as a chemical to remove iron and hydrogen sulfide from well water via a Manganese Greensand Filter. Pot-Perm is also obtainable at pool supply stores and is used additionally to treat waste water, historically it was used to disinfect drinking water and can turn the water pink. It currently finds application in the control of nuisance organisms such as zebra mussels in fresh water collection, aside from its use in water treatment, the other major application of KMnO4 is as a reagent for the synthesis of organic compounds. Significant amounts are required for the synthesis of ascorbic acid, chloramphenicol, saccharin, isonicotinic acid, potassium permanganate can be used to quantitatively determine the total oxidisable organic material in an aqueous sample. The value determined is known as the permanganate value, in analytical chemistry, a standardized aqueous solution of KMnO4 is sometimes used as an oxidizing titrant for redox titrations. In a related way, it is used as a reagent to determine the Kappa number of wood pulp, for the standardization of KMnO4 solutions, reduction by oxalic acid is often used. Aqueous, acidic solutions of KMnO4 are used to collect gaseous mercury in flue gas during stationary source emissions testing, in histology, potassium permanganate was used as a bleaching agent. Ethylene absorbents extend storage time of bananas even at high temperatures and this effect can be exploited by packing bananas in polyethylene together with potassium permanganate
11.
European Chemicals Agency
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ECHA is the driving force among regulatory authorities in implementing the EUs chemicals legislation. ECHA helps companies to comply with the legislation, advances the safe use of chemicals, provides information on chemicals and it is located in Helsinki, Finland. The Agency, headed by Executive Director Geert Dancet, started working on 1 June 2007, the REACH Regulation requires companies to provide information on the hazards, risks and safe use of chemical substances that they manufacture or import. Companies register this information with ECHA and it is freely available on their website. So far, thousands of the most hazardous and the most commonly used substances have been registered, the information is technical but gives detail on the impact of each chemical on people and the environment. This also gives European consumers the right to ask whether the goods they buy contain dangerous substances. The Classification, Labelling and Packaging Regulation introduces a globally harmonised system for classifying and labelling chemicals into the EU. This worldwide system makes it easier for workers and consumers to know the effects of chemicals, companies need to notify ECHA of the classification and labelling of their chemicals. So far, ECHA has received over 5 million notifications for more than 100000 substances, the information is freely available on their website. Consumers can check chemicals in the products they use, Biocidal products include, for example, insect repellents and disinfectants used in hospitals. The Biocidal Products Regulation ensures that there is information about these products so that consumers can use them safely. ECHA is responsible for implementing the regulation, the law on Prior Informed Consent sets guidelines for the export and import of hazardous chemicals. Through this mechanism, countries due to hazardous chemicals are informed in advance and have the possibility of rejecting their import. Substances that may have effects on human health and the environment are identified as Substances of Very High Concern 1. These are mainly substances which cause cancer, mutation or are toxic to reproduction as well as substances which persist in the body or the environment, other substances considered as SVHCs include, for example, endocrine disrupting chemicals. Companies manufacturing or importing articles containing these substances in a concentration above 0 and they are required to inform users about the presence of the substance and therefore how to use it safely. Consumers have the right to ask the retailer whether these substances are present in the products they buy, once a substance has been officially identified in the EU as being of very high concern, it will be added to a list. This list is available on ECHA’s website and shows consumers and industry which chemicals are identified as SVHCs, Substances placed on the Candidate List can then move to another list
12.
Phthalic anhydride
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Phthalic anhydride is the organic compound with the formula C6H42O. It is the anhydride of phthalic acid, Phthalic anhydride is a principal commercial form of phthalic acid. It was the first anhydride of an acid to be used commercially. This colourless solid is an important industrial chemical, especially for the production of plasticizers for plastics. In 2000, the production volume was estimated to be about 3 million tonnes per year. Phthalic anhydride was first reported in 1836 by Auguste Laurent, more contemporary routes include catalytic oxidation of ortho-xylene and naphthalene, although use of naphthalene has declined. Starting from o-xylene, the oxidation follows the following stoichiometry, C6H42 +3 O2 → C6H42O +3 H2O The reaction proceeds with about 70% selectivity. About 10% of maleic anhydride is produced, C6H42 +7.5 O2 → C4H2O3 +4 H2O +4 CO2 The reaction is catalyzed by a vanadium pentoxide between 320 -400 °C. The phthalic anhydride is separated from byproducts by a series of switch condensers, Phthalic anhydride and maleic anhydride are recovered by distillation. Phthalic anhydride can also be prepared from phthalic acid, The primary use of phthalic anhydride is as an intermediate in the production of plastics from vinyl chloride. Phthalate esters, which function as plasticizers, are derived from Phthalic Anhydride, phthalate plasticizers are used for the production of flexible PVC products such as cables, pipes and hoses, leather cloth, shoes, film for packaging etc. It is also utilized as a rubber scorch inhibitor and retarder, Phthalic anhydride is a versatile intermediate in organic chemistry, in part because it is bifunctional and cheaply available. Hydrolysis by hot water forms ortho-phthalic acid, hydrolysis of anhydrides is not typically a reversible process. Phthalic acid is easily dehydrated to form phthalic anhydride. Above 180 °C, phthalic anhydride re-forms, as with other anhydrides, the alcoholysis reaction is the basis of the manufacture of phthalate esters, which are widely used plasticizers. In the 1980s, approximately 6. 5×109 kg of these esters were produced annually, Phthalic anhydride is a precursor to a variety of reagents useful in organic synthesis. Important derivatives include phthalimide and its many derivatives, chiral alcohols form half-esters, and these derivatives are often resolvable because they form diastereomeric salts with chiral amines such as brucine. Phthalic anhydride is used in industry for the production of certain dyes
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Chisholm, Hugh, ed. (1911). "Phthalic Acids". Encyclopædia Britannica. 21 (11th ed.). Cambridge University Press. pp. 545–546.
Chisholm, Hugh, ed. (1911). "