Pierson College is a residential college at Yale University in New Haven, Connecticut. Opened in 1933, it is named for Abraham Pierson, a founder and the first rector of the Collegiate School, the college later known as Yale. With just under 500 undergraduate members, Pierson is the largest of Yale's residential colleges by number of students.

Yale University has a system of fourteen residential colleges with which all Yale undergraduate students and many faculty are affiliated. Inaugurated in 1933, the college system is considered the defining feature of undergraduate life at Yale College, and the residential colleges serve as the residence halls and social hubs for most undergraduates. Construction and programming for eight of the original ten colleges were funded by educational philanthropist Edward S. Harkness. Yale was, along with Harvard, one of the first universities in the United States to establish a residential college system.