Piggly Wiggly is an American supermarket chain operating in the American Southern and Midwestern regions run by Piggly Wiggly, LLC, an affiliate of C&S Wholesale Grocers. Its first outlet opened in 1916 in Memphis, Tennessee, and is notable as the first true self-service grocery store, and the originator of various familiar supermarket features such as checkout stands, individual item price marking and shopping carts. The company headquarters is in Keene, New Hampshire. As of 2024, 503 independently owned Piggly Wiggly stores currently operate across 18 states, primarily in smaller cities and towns.

A supermarket is a self-service shop offering a wide variety of food, beverages and household products, organized into sections. This kind of store is larger and has a wider selection than earlier grocery stores, but is smaller and more limited in the range of merchandise than a hypermarket or big-box market. In everyday United States usage, however, "grocery store" is often used to mean "supermarket".