Pinky and the Brain is an American animated sitcom created by Tom Ruegger for the Kids' WB programming block of The WB. It was the first animated television series to be presented in Dolby Surround and a collaboration of Steven Spielberg with his production company Amblin Television and Warner Bros. Animation. The characters first appeared in 1993 as a recurring segment on the animated television series Animaniacs. It was later spun off as a series due to its popularity, with 65 episodes produced. The characters later appeared in the series Pinky, Elmyra & the Brain, and later returned to their roots as an Animaniacs segment in the 2020 revival of that series.

Robert Frederick Paulsen III is an American voice actor and voice director, known for his roles in numerous animated television series and films. He received a Daytime Emmy Award for Outstanding Performer in an Animated Program and three Annie Awards for his role as both Yakko and Pinky in the Animaniacs franchise. His other voice roles include Hadji in The New Adventures of Jonny Quest (1986–1987) and The Real Adventures of Jonny Quest (1996–1997); Raphael in Teenage Mutant Ninja Turtles (1987–1996); P.J. Pete in Goof Troop (1992), A Goofy Movie (1995), and An Extremely Goofy Movie (2000); Jaq in Cinderella II: Dreams Come True (2002) and Cinderella III: A Twist in Time (2007); and Mac in The Looney Tunes Show (2011–2013) and Looney Tunes: Rabbits Run (2015).