Pinky and the Brain is an American animated sitcom created by Tom Ruegger for the Kids' WB programming block of The WB. It was the first animated television series to be presented in Dolby Surround and a collaboration of Steven Spielberg with his production company Amblin Television and Warner Bros. Animation. The characters first appeared in 1993 as a recurring segment on the animated television series Animaniacs. It was later spun off as a series due to its popularity, with 65 episodes produced. The characters later appeared in the series Pinky, Elmyra & the Brain, and later returned to their roots as an Animaniacs segment in the 2020 revival of that series.

The Acme Corporation is a fictional corporation that features prominently in the Road Runner/Wile E. Coyote animated shorts as a running gag. The company manufactures outlandish products that fail or backfire catastrophically at the worst possible times. The name is also used as a generic title in many cartoons, especially those made by Warner Bros. and films, TV series, commercials and comic strips.