The Milvian Bridge is a bridge over the Tiber in northern Rome, Italy. It was an economically and strategically important bridge in the era of the Roman Empire and was the site of the famous Battle of the Milvian Bridge in 312 AD, which led to the imperial rule of Constantine.

The Tiber is the third-longest river in Italy and the longest in Central Italy, rising in the Apennine Mountains in Emilia-Romagna and flowing 406 km (252 mi) through Tuscany, Umbria, and Lazio, where it is joined by the River Aniene, to the Tyrrhenian Sea, between Ostia and Fiumicino. It drains a basin estimated at 17,375 km2 (6,709 sq mi). The river has achieved lasting fame as the main watercourse of the city of Rome, which was founded on its eastern banks.