Pope Gregory XI was head of the Catholic Church from 30 December 1370 to his death, in March 1378. He was the seventh and last Avignon pope and the most recent French pope recognized by the modern Catholic Church. In 1377, Gregory XI returned the Papal court to Rome, ending nearly 70 years of papal residency in Avignon, France. His death was swiftly followed by the Western Schism involving two Avignon-based antipopes.

The Avignon Papacy was the period from 1309 to 1376 during which seven successive popes resided in Avignon rather than in Rome. The situation arose from the conflict between the papacy and the French crown, culminating in the death of Pope Boniface VIII after his arrest and maltreatment by Philip IV of France. Following the subsequent death of Pope Benedict XI, Philip forced a deadlocked conclave to elect the French Clement V as pope in 1305. Clement refused to move to Rome, and in 1309 he moved his court to the papal enclave at Avignon, where it remained for the next 67 years. This absence from Rome is sometimes referred to as the "Babylonian captivity of the Papacy".