Prescot Parish Church, also known as St Mary's Church, is in the town of Prescot, Merseyside, England. It is recorded in the National Heritage List for England as a designated Grade I listed building, and is an active Anglican parish church.

Prescot is a town and civil parish within the Metropolitan Borough of Knowsley in Merseyside, United Kingdom. It lies about eight miles (13 km) to the east of Liverpool city centre. At the 2001 Census, the civil parish population was 11,184. The population of the larger Prescot East and West wards at the 2011 census totalled 14,139. Prescot marks the beginning of the A58 road which runs through to Wetherby, near Leeds in West Yorkshire. The town is served by Prescot railway station and Eccleston Park railway station in neighbouring Eccleston.