Presque Isle is the commercial center and largest city in Aroostook County, Maine, United States. The population was 8,797 at the 2020 Census. The city is home to the University of Maine at Presque Isle, Northern Maine Community College, Northern Maine Fairgrounds, the Aroostook Centre Mall, and the Presque Isle International Airport.

Double Eagle II, piloted by Ben Abruzzo, Maxie Anderson and Larry Newman, became the first balloon to cross the Atlantic Ocean when it landed 17 August 1978 in Miserey near Paris, 137 hours 6 minutes after leaving Presque Isle, Maine.