Preston is a town in Chenango County, New York, United States. The population was 1,044 at the 2010 census. Preston is an interior town of Chenango County and is west of the city of Norwich.

Chenango County is a county located in the south-central section U.S. state of New York. As of the 2020 census, the population was 47,220. Its county seat is Norwich. The county's name originates from an Oneida word meaning 'large bull-thistle'. The county is part of the Southern Tier region of the state.