The Prince-Bishopric of Osnabrück was an ecclesiastical principality of the Holy Roman Empire from 1225 until 1803. It should not be confused with the Diocese of Osnabrück, which was larger and over which the prince-bishop exercised only the spiritual authority of an ordinary bishop. It was named after its capital, Osnabrück.

Count Franz von Waldeck was Prince-Bishop of Münster, Osnabrück, and Minden in the Lower Rhenish–Westphalian Circle of the Holy Roman Empire. He suppressed the Münster Rebellion, a millenarian Anabaptist theocratic insurrection which occupied the fortified city of Münster.