The Prince of Wales Island, or Muralag, is an island of the Torres Strait Islands archipelago at the tip of Cape York Peninsula within the Endeavour Strait of Torres Strait in Queensland, Australia. The island is situated approximately 20 km (12 mi) north of Muttee Heads which is adjacent to Bamaga and south of Thursday Island. It is within the locality of Prince Of Wales within the Shire of Torres. In the 2021 census, Prince Of Wales had a population of 62 people.

The Torres Strait, also known as Zenadh Kes, is a strait between Australia and the Melanesian island of New Guinea. It is 150 km (93 mi) wide at its narrowest extent. To the south is Cape York Peninsula, the northernmost extremity of the Australian mainland. To the north is the Western Province of Papua New Guinea. It is named after the Spanish navigator Luís Vaz de Torres, who sailed through the strait in 1606.