Prince station is an Amtrak station in Prince, West Virginia, served by the Cardinal. It serves as the main depot for the Beckley area because it is on the CSX mainline while Beckley itself is not.

The Cardinal is a long-distance passenger train operated by Amtrak between New York Penn Station and Chicago Union Station via Philadelphia, Washington, D.C., Charlottesville, Charleston, Huntington, Cincinnati, and Indianapolis. Along with the Capitol Limited and Lake Shore Limited, it is one of three trains linking the Northeast and Chicago. Its 1,146-mile (1,844 km) trip between New York and Chicago takes 281⁄4 hours.