Proteasome
Videos
Proteasomes are essential protein complexes responsible for the degradation of proteins by proteolysis, a chemical reaction that breaks peptide bonds. Enzymes that help such reactions are called prote
Cartoon representation of the 26S proteasome.
Three distinct conformational states of the 26S proteasome. The conformations are hypothesized to be responsible for recruitment of the substrate, its irreversible commitment, and finally processing and translocation into the core particle, where degradation occurs.
The crystal structure of yeast Rpn11/8 heterodimer bound to WT Ubiquitin. Rpn11 is in green, Rpn8 is in grey, and Ubiquitin is shown in pink.
Protein
Videos
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metab
Proteasome
…Proteasomes are essential protein complexes responsible for the degradation of proteins by proteolysis, a chemical reaction that breaks peptide bonds. Enzymes that help such reactions are called proteases. Proteasomes are found inside all…
Polypeptide
John Kendrew with model of myoglobin in progress
Proteins in various cellular compartments and structures tagged with green fluorescent protein (here, white)
Constituent amino-acids can be analyzed to predict secondary, tertiary and quaternary protein structure, in this case hemoglobin containing heme units.