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Proteoglycan
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Proteoglycans are proteins that are heavily glycosylated. The basic proteoglycan unit consists of a "core protein" with one or more covalently attached glycosaminoglycan chain. The point of attachment
Aggrecan, the major proteoglycan in cartilage, has 2316 amino acids
Aggrecan, the major proteoglycan in cartilage, has 2316 amino acids
Golgi apparatus
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The Golgi apparatus, also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells. Part of the endomembrane system in the cytoplasm, it packages pro
Proteoglycan
…is synthesized by ribosomes and translocated into the lumen of the rough endoplasmic reticulum. Glycosylation of the proteoglycan occurs in the Golgi apparatus in multiple enzymatic steps. First, a special link tetrasaccharide is attached to a serine side chain on the core protein to serve as a primer for…
Three-dimensional projection of a mammalian Golgi stack imaged by confocal microscopy and volume surface rendered using Imaris software. Taken from th
Three-dimensional projection of a mammalian Golgi stack imaged by confocal microscopy and volume surface rendered using Imaris software. Taken from the movie.