Province of Santa Cruz de Tenerife, also Province of Santa Cruz, is a province of Spain, consisting of the western part of the autonomous community of the Canary Islands. It consists of about half of the Atlantic archipelago: the islands of Tenerife, La Gomera, El Hierro, and La Palma. It occupies an area of 3,381 km2 (1,305 sq mi). It also includes a series of adjacent roques.

The Canary Islands, also known informally as the Canaries, are a Spanish autonomous community and archipelago in Macaronesia in the Atlantic Ocean. At their closest point to the African mainland, they are 100 kilometres west of Morocco and the Western Sahara. They are the southernmost of the autonomous communities of Spain. The islands have a population of 2.2 million people and are the most populous special territory of the European Union.