Ptolemy VI Philometor was a Greek king of Ptolemaic Egypt who reigned from 180 to 164 BC and from 163 to 145 BC. He is often considered the last ruler of ancient Egypt when that state was still a major power.

The Ptolemaic Kingdom or Ptolemaic Empire was an Ancient Greek polity based in Egypt during the Hellenistic period. It was founded in 305 BC by the Macedonian general Ptolemy I Soter, a companion of Alexander the Great, and ruled by the Ptolemaic dynasty until the death of Cleopatra VII in 30 BC. Reigning for nearly three centuries, the Ptolemies were the longest and final dynasty of ancient Egypt, heralding a distinctly new era for religious and cultural syncretism between Greek and Egyptian culture.