The Purdue Boilermakers football team represents Purdue University in the NCAA Football Bowl Subdivision (FBS) of college football. Purdue plays its home games at Ross–Ade Stadium on the campus of Purdue University in West Lafayette, Indiana. The head coach of Purdue is Ryan Walters, the 37th head coach in Purdue history. The Boilermakers compete in the Big Ten Conference as a member of the West Division. Purdue had most recently been a part of the Leaders Division of the Big Ten, but moved to the West Division in 2014 due to conference expansion.

The Chicago Maroons football team represents the University of Chicago in college football. The Maroons, which play in NCAA Division III, have been a football-only member of the Midwest Conference since 2017. The University of Chicago was a founding member of the Big Ten Conference and the Maroons were coached by Amos Alonzo Stagg for 41 seasons. In 1935, halfback Jay Berwanger became the first recipient of the Downtown Athletic Club Trophy, later known as the Heisman Trophy. In the late 1930s, university president Robert Maynard Hutchins decided that big-time college football and the university's commitment to academics were not compatible. The university abolished its football program in 1939 and withdrew from the Big Ten in 1946. Football returned to the University of Chicago in 1963 in the form of a club team, which was upgraded to varsity status in 1969. The Maroons began competing in Division III in 1973.